SecProbe.io

June 22, 2015

Via E -mail
Cameron Reynolds
President, Principal Executive Officer and Director
VolitionRx Limited
1 Scotts Road
#24-05 Shaw Centre
Singapore 228208

Re: VolitionRx  Limited
  Post-Effective Amendment No. 1 to Form S -1 on Form S-3
Filed  June 12, 2015
  File No.  333-195213

Dear Mr. Reynolds :

This is to advise you that we have not  reviewed and will not review your registration
statement .

We urge all persons who are responsible for the accuracy and adequacy of the disclosure
in the filing to be certain that the filing includes the information the Securities Act of 193 3 and
all applicable Securities  Act rules require.   Since the company and its management are  in
possession of all facts relating to a company’s disclosure, they are responsible for the accuracy
and adequacy of the disclosures they have made.

In the event you request acceleration of the effective date of the pending regist ration
statement , please provide  a written statement from the company acknowledging that:

 should the Commission or the staff, acting pursuant to delegated authority, declare the
filing effective, it does not foreclose the Commission from taking any action wit h respect
to the filing;

 the action of the Commission or the staff, acting pursuant to delegated authority, in
declaring the filing effective, does not relieve the company from its full responsibility for
the adequacy and accuracy of the disclosure in th e filing; and

 the company may not assert staff comments and the declaration of effectiveness as a
defense in any proceeding initiated by the Commission or any person under the federal
securities laws of the United States.

Cameron  Reynolds
VolitionRx Limited
June 22, 2015
Page 2

 Please refer to Rules 460 and 461 regarding requests for  acceleration .  We will consider a
written request for acceleration of the effective date of the registration statement as confirmation
of the fact that those requesting acceleration are aware of their respective responsibilities under
the Securities Act of 1933 and the Securities Exchange Act of 1934 as they relate to the proposed
public offering of the registered securities .

Please  contact Christina De Rosa at (202) 551 -3577 or me  at (202) 551 -3715  with any
questions.

Sincerely,

 /s/ Daniel  Greenspan for

 Jeffrey P. Riedler
Assistant Director

cc: Via E -mail
            Marc G. Alcser, Esq.
            Stradling Yocca Carlson & Rauth, P.C.
            660 Newport Center Drive, Suite 1600
            Newport Beach, California 92660