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CORRESP Filing

AETHLON MEDICAL INC
Date: Dec. 30, 2025 · CIK: 0000882291 · Accession: 0001683168-25-009432

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File numbers found in text: 333-292405

Date
December 30, 2025
Author
James B. Frakes
Form
CORRESP
Company
AETHLON MEDICAL INC

Letter

Aethlon Medical, Inc.

11555 Sorrento Valley Road, Suite 203

San Diego, CA 92121

December 30, 2025

VIA EDGAR

United States Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

Re:

Aethlon Medical, Inc.

Registration Statement on Form S-3 Filed December 23, 2025

File No. 333-292405

Ladies and Gentlemen:

Pursuant to Rule 461 under the Securities Act of 1933, as amended (the "Securities Act"), Aethlon Medical, Inc., a Nevada corporation (the "Registrant"), hereby respectfully requests that the United States Securities and Exchange Commission (the "Commission") take appropriate action to cause the above-referenced Registration Statement on Form S-3 (File No. 333-292405) to become effective on Friday, January 2, 2026, at 5:00 p.m., Eastern Time, or as soon thereafter as is practicable.

The Registrant understands that the Commission will consider this request as a confirmation by the Registrant that it is aware of its responsibilities under the federal securities laws as they relate to the issuance of the securities covered by the Registration Statement.

The Registrant hereby authorizes its counsel, Dennis J. Doucette, Esq. of Procopio, Cory, Hargreaves & Savitch LLP, to orally modify or withdraw this request for acceleration. Please contact Mr. Doucette at (858) 720-6322 with any questions you may have concerning this request, and please notify him when this request for acceleration has been granted.

Sincerely,
AETHLON MEDICAL, INC.

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CORRESP
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 Aethlon Medical, Inc.

 11555 Sorrento Valley
Road, Suite 203

 San Diego, CA 92121

 December 30, 2025

 VIA EDGAR

 United States Securities and Exchange
Commission

 Division of Corporation Finance

 100 F Street, N.E.

 Washington, D.C. 20549

 Re:

 Aethlon Medical, Inc.

 Registration Statement on Form S-3
 Filed December 23, 2025

 File No. 333-292405

 Ladies and Gentlemen:

 Pursuant to Rule 461 under the Securities Act
of 1933, as amended (the "Securities Act"), Aethlon Medical, Inc., a Nevada corporation (the "Registrant"), hereby
respectfully requests that the United States Securities and Exchange Commission (the "Commission") take appropriate action
to cause the above-referenced Registration Statement on Form S-3 (File No. 333-292405) to become effective on Friday, January 2, 2026,
at 5:00 p.m., Eastern Time, or as soon thereafter as is practicable.

 The Registrant understands that the Commission
will consider this request as a confirmation by the Registrant that it is aware of its responsibilities under the federal securities laws
as they relate to the issuance of the securities covered by the Registration Statement.

 The Registrant hereby authorizes its counsel,
Dennis J. Doucette, Esq. of Procopio, Cory, Hargreaves & Savitch LLP, to orally modify or withdraw this request for acceleration.
Please contact Mr. Doucette at (858) 720-6322 with any questions you may have concerning this request, and please notify him when this
request for acceleration has been granted.

 Sincerely,

 AETHLON MEDICAL, INC.

 /s/ James B. Frakes

 James B. Frakes

 Chief Executive Officer and Chief Financial Officer