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VIA
EDGAR

June
7, 2024

United
States Securities and Exchange Commission

Office
of Life Sciences

Division
of Corporation Finance

100
F Street, N.E.

Washington,
D.C. 20549

    Re:
    Ainos,
    Inc.

    Acceleration
    Request for Registration Statement on Form S-3

    File
    No. 333-279880

Ladies
and Gentlemen:

Pursuant
to Rule 461 under the Securities Act of 1933, as amended (the “Act”), Ainos, Inc. (the “Company”)
hereby requests that the effective date of the above-referenced registration statement (the “Registration Statement”)
be accelerated to June 11, 2024, at 4:30 p.m., Eastern Time, or as soon thereafter as practicable, unless we or our outside counsel,
Lucosky Brookman LLP, request by telephone that such Registration Statement be declared effective at some other time. In making this
acceleration request, the Company acknowledges that it is aware of its responsibilities under the Act.

Once
the Registration Statement is effective, please orally confirm the event with the Company by calling Lawrence K. Lin at 310-869-4870.
If you have any questions regarding this request, please contact Lawrence K. Lin at 310-869-4870.

    Sincerely,

    Ainos,
    Inc.

    /s/
    Chun-Hsien Tsai

    Chun-Hsien
    Tsai

    Chairman
    of the Board, President and Chief Executive Officer

    cc:
    Christopher
    Hsin-Liang Lee

    Steven
    A. Lipstein, Esq.