SecProbe.io

July 8 , 2015

Via E-Mail
Michael P. Gray
Chief Business and Financial Officer
Curis, Inc.
4 Maguire Road
Lexington, Massachusetts 02421

Re: Curis, Inc.
  Registration Statement on Form S -3
Filed July 2 , 2015
  File No. 333-205460

Dear Mr. Gray :

We have limited our review of your registration statement to the resolution of your
pending confidential treatment request. Please be advised that we will not be in a position to
declare your registration statement effective until all outstanding comments, if any, on your
request for confidential treatment have been cleared.

We urge all persons who are responsible for the accuracy and adequacy of the disclosure
in the filing to be certain  that the filing includes the information the Securities Act of 193 3 and
all applicable Securities  Act rules require.   Since the company and its management are in
possession of all facts relating to a company’s disclosure, they are responsible for the accu racy
and adequacy of the disclosures they have made.

Notwithstanding our comment , in the event you request acceleration of the effective date
of the pending registration statement , please provide a written statement from the company
acknowledging that:

 should the Commission or the staff, acting pursuant to delegated authority, declare the
filing effective, it does not foreclose the Commission from taking any action with respect
to the filing;

 the action of the Commission or the staff, acting pursuant  to delegated authority, in
declaring the filing effective, does not relieve the company from its full responsibility for
the adequacy and accuracy of the disclosure in the filing; and

 the company may not assert staff comments and the declaration of effe ctiveness as a
defense in any proceeding initiated by the Commission or any person under the federal
securities laws of the United States.

Michael P. Gray
Curis, Inc.
July 8 , 2015
Page 2

Please refer to Rules 460 and 461 regarding requests for  acceleration .  We will consider a
written request for accel eration of the effective date of the registration statement as confirmation
of the fact that those requesting acceleration are aware of their respective responsibilities under
the Securities Act of 1933 and the Securities Exchange Act of 1934 as they relat e to the proposed
public offering of the securities specified in the above registration statement.  Please allow
adequate time  for us to review any amendment prior to the requested effective date of the
registration statement.

You may contact P reston  Brewer at (202) 551 -3969 , Dan Greenspan at (202) 551 -3623  or
me at (202) 551 -3715 with any questions.

Sincerely,

 /s/ Jeffrey P. Riedler

 Jeffrey P. Riedler
 Assistant Director

cc: Via E -Mail
 Cynthia T. Mazareas , Esq.
 Wilmer Cutler Pickering Hale and Dorr LLP