SEC Company Response from YIELD10 BIOSCIENCE, INC. (YTEN) (CIK 0001121702) — Jul 12, 2023

YIELD10 BIOSCIENCE, INC. (YTEN) (CIK 0001121702)
Date: July 12, 2023 · CIK: 0001121702 · Accession: 0001104659-23-080320

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File numbers found in text: 333-273070

Date

July 12, 2023

Author

Form

CORRESP

Company

YIELD10 BIOSCIENCE, INC. (YTEN) (CIK 0001121702)

Letter

Via Edgar United States Securities and Exchange Commission Division of Corporation Finance Attn: Nicholas O’Leary, Esq. Registration Statement on Form S-1 (File No. 333-273070) Request for Acceleration

Re: Yield10 Bioscience, Inc.

Dear Mr. O’Leary:

This letter is sent on behalf of Yield10 Bioscience, Inc. (the “Company”) in connection with the above-referenced Registration Statement on Form S-1 (the “Registration Statement”) filed with the Securities and Exchange Commission (the “Commission”) by the Company pursuant to the Securities Act of 1933, as amended (the “Securities Act”). Pursuant to Rule 461 promulgated under the Securities Act, the Company hereby requests that the effective date of the Registration Statement be accelerated to 4:00 p.m., Eastern Time, on July 14, 2023, or as soon thereafter as practicable.

Please contact Joel I. Papernik of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C., at (212) 935-3000, with any questions you may have concerning this request.

Sincerely,
Yield10 Bioscience, Inc.

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CORRESP
1
filename1.htm

July 12, 2023

Via
Edgar

United States Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

 Attn: Nicholas O’Leary, Esq.

 Re: Yield10 Bioscience, Inc.

Registration Statement
on Form S-1 (File No. 333-273070)

Request for Acceleration

Dear Mr. O’Leary:

This letter is sent on
behalf of Yield10 Bioscience, Inc. (the “Company”) in connection with the above-referenced Registration Statement on
Form S-1 (the “Registration Statement”) filed with the Securities and Exchange Commission (the “Commission”)
by the Company pursuant to the Securities Act of 1933, as amended (the “Securities Act”). Pursuant to Rule 461 promulgated
under the Securities Act, the Company hereby requests that the effective date of the Registration Statement be accelerated to 4:00 p.m.,
Eastern Time, on July 14, 2023, or as soon thereafter as practicable.

Please contact Joel I.
Papernik of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C., at (212) 935-3000, with any questions you may have concerning this request.

    Sincerely,

    Yield10 Bioscience, Inc.

    By:
    /s/ Oliver P. Peoples, Ph.D.

    Name:
    Oliver P. Peoples, Ph.D.

    Title:
    President and Chief Executive Officer

cc:            Joel I. Papernik, Mintz,
Levin, Cohn, Ferris, Glovsky and Popeo, P.C.

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