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SEC Company Response from SCYNEXIS (SCYX) — May 6, 2026

SCYNEXIS INC
Date: May 6, 2026 · CIK: 0001178253 · Accession: 0001193125-26-208907

Offering / Registration Process

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File numbers found in text: 333-295493

Date
May 6, 2026
Author
Chief Legal Officer
Form
CORRESP
Company
SCYNEXIS INC

Letter

RE: SCYNEXIS, Inc. Registration Statement on Form S-3 (File No. 333-295493) Request for Acceleration of Effective Date Ladies and Gentlemen: SCYNEXIS, Inc. (the “ Registrant ”) hereby requests that the U.S. Securities and Exchange Commission (the “ Commission ”) take appropriate action to cause the above-referenced Registration Statement on Form S-3 (File No. 333-295493) (the “ Registration Statement ”) to become effective on Friday, May 8, 2026, at 4:30 p.m. Eastern Time, or as soon thereafter as is practicable or at such later time as the Registrant may orally request via telephone call to the staff of the Commission. The Registrant hereby authorizes each of Matthew Hemington and Allison Pang of Cooley LLP, counsel to the Registrant, to make such request on its behalf. Once the Registration Statement has been declared effective, please orally confirm that event with Matthew Hemington of Cooley LLP, counsel to the Registrant, at (650) 843-5062, or in his absence, Allison Pang, at (650) 843-5315. [Remainder of page intentionally left blank]

SCYNEXIS, I NC . 1 Evertrust Plaza, 13th Floor Jersey City, NJ 07302 May 6, 2026 VIA EDGAR Securities and Exchange Commission Office of Finance Division of Corporation Finance 100 F. Street N.E. Washington, D.C. 20549-3010

Very truly yours,
SCYNEXIS, I NC .

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CORRESP
 1
 filename1.htm

 CORRESP

 SCYNEXIS, I NC .
 1 Evertrust Plaza, 13th Floor
 Jersey City, NJ 07302 May 6, 2026
 VIA EDGAR Securities and Exchange Commission
 Office of Finance Division of Corporation Finance
 100 F. Street N.E. Washington, D.C. 20549-3010

 RE:
 SCYNEXIS, Inc.
 Registration Statement on Form S-3 (File
 No. 333-295493) Request for Acceleration of Effective Date
 Ladies and Gentlemen: SCYNEXIS, Inc. (the
“ Registrant ”) hereby requests that the U.S. Securities and Exchange Commission (the “ Commission ”) take appropriate action to cause the above-referenced Registration Statement on Form S-3 (File No. 333-295493) (the “ Registration Statement ”) to become effective on Friday, May 8, 2026, at 4:30 p.m. Eastern Time, or as soon
thereafter as is practicable or at such later time as the Registrant may orally request via telephone call to the staff of the Commission. The Registrant hereby authorizes each of Matthew Hemington and Allison Pang of Cooley LLP, counsel to the
Registrant, to make such request on its behalf. Once the Registration Statement has been declared effective, please orally confirm that
event with Matthew Hemington of Cooley LLP, counsel to the Registrant, at (650) 843-5062, or in his absence, Allison Pang, at (650) 843-5315.
 [Remainder of page intentionally left blank]

 Very truly yours,

 SCYNEXIS, I NC .

 By:

 /s/ Scott Sukenick

 Name:

 Scott Sukenick

 Title:

 Chief Legal Officer

 cc:
 Matthew Hemington, Cooley LLP
 Allison Pang, Cooley LLP