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SEC Company Response from ALNYLAM PHARMACEUTICALS, INC. (ALNY) (CIK 0001178670) (ALNY) — Dec 8, 2010

ALNYLAM PHARMACEUTICALS, INC. (ALNY) (CIK 0001178670)
Date: Dec. 8, 2010 · CIK: 0001178670 · Accession: 0000950123-10-111845

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File numbers found in text: 000-50743

Date
December 8, 2010
Author
/s/ Clark W. Petschek
Form
CORRESP
Company
ALNYLAM PHARMACEUTICALS, INC. (ALNY) (CIK 0001178670)

Letter

Division of Corporate Finance Attention: Johnny Gharib Alnylam Pharmaceuticals, Inc. Form 10-K Filed February 26, 2010 File No. 000-50743

Re:

Dear Mr. Gharib:

This letter relates to the letter, dated December 2, 2010 (the “Letter”), from Jeffrey Riedler of the Staff of the U.S. Securities and Exchange Commission to John M. Maraganore, Chief Executive Officer of Alnylam Pharmaceuticals, Inc. (the “Company”).

On behalf of the Company, and as discussed by telephone with you on December 7, 2010, this letter confirms that the Company will respond to the Letter on or before January 13, 2011.

If you require additional information, please do not hesitate to contact me at 617-526-6443.

Sincerely,
/s/ Clark W. Petschek

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CORRESP
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corresp

December 8, 2010

By EDGAR Submission

U.S. Securities and Exchange Commission

Division of Corporate Finance

100 F Street, N.E., Mail Stop 6010

Washington, D.C. 20549

Attention: Johnny Gharib

    Re:

    Alnylam Pharmaceuticals, Inc.

Form 10-K

Filed February 26, 2010

File No. 000-50743

Dear Mr. Gharib:

This letter relates to the letter, dated December 2, 2010 (the “Letter”), from Jeffrey Riedler of
the Staff of the U.S. Securities and Exchange Commission to John M. Maraganore, Chief Executive
Officer of Alnylam Pharmaceuticals, Inc. (the “Company”).

On behalf of the Company, and as discussed by telephone with you on December 7, 2010, this letter
confirms that the Company will respond to the Letter on or before January 13, 2011.

If you require additional information, please do not hesitate to contact me at 617-526-6443.

Sincerely,

    /s/ Clark W. Petschek

    Clark W. Petschek

    cc:

    Philip T. Chase, Esq.

Lia Der Marderosian, Esq.