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SEC Company Response from ALNYLAM PHARMACEUTICALS, INC. (ALNY) (CIK 0001178670) (ALNY) — Jan 19, 2018

ALNYLAM PHARMACEUTICALS, INC. (ALNY) (CIK 0001178670)
Date: Jan. 19, 2018 · CIK: 0001178670 · Accession: 0001193125-18-014819

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File numbers found in text: 001-36407

Referenced dates: December 11, 2017, January 8, 2018

Date
January 19, 2018
Author
/s/ Michael P. Mason
Form
CORRESP
Company
ALNYLAM PHARMACEUTICALS, INC. (ALNY) (CIK 0001178670)

Letter

United States Securities and Exchange Commission Division of Corporation Finance Attention: Frank Wyman and Jim Rosenberg, Office of Healthcare & Insurance Alnylam Pharmaceuticals, Inc. Form 10-K for Fiscal Year Ended December 31, 2016 Filed February 15, 2017 File No. 001-36407

Dear Messrs. Wyman and Rosenberg:

This letter is being furnished in response to the comments of the staff (the “Staff”) of the Securities and Exchange Commission (the “Commission”) in the Commission’s letter dated January 8, 2018 (the “Comment Letter”) to Michael P. Mason, Vice President of Finance and Treasurer of Alnylam Pharmaceuticals, Inc. (the “Company”), with respect to the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2016, and the documents incorporated by reference therein. The responses set forth below have been organized in the same manner in which the Commission’s comments and headings were organized in the Comment Letter.

Comment: Notes to the Consolidated Financial Statements – 3. Significant Agreements, page 97

We acknowledge the information provided in your response to our prior comment 1 of our November 27, 2017 comment letter. As required by ASC 730-20-50-1b, please confirm to us that you will disclose herein the costs incurred for each of your significant agreements. We would expect the amount disclosed to include the costs you provided in your response and your reasonable estimate of other costs incurred albeit for which you may not track separately for each agreement. In this regard, it would appear that a reasonable estimate would be attainable, given that you track hours incurred for the purpose of billing your counterparties. Finally, we believe additional disclosure in your research and development expense discussion of your MD&A of the nature and amount of research and development costs incurred related to your agreements would be informative.

Response

In future periodic filings, including the Form 10-K for the fiscal year ended December 31, 2017, the Company will revise its disclosure to disclose the costs incurred for each of the Company’s significant agreements, including the costs provided in the Company’s response letter dated December 11, 2017, and a reasonable estimate of other costs incurred, and the Company will include additional disclosure in the research and development expense discussion of MD&A of the nature and amount of research and development costs incurred related to its significant agreements.

Messrs. Frank Wyman and Jim Rosenberg

U.S. Securities and Exchange Commission

January 19, 2018

Page 2

If you have any questions with regard to the Company’s responses or would like to discuss any of the matters covered in this letter, please contact the undersigned at (617) 551-8200 or Gregg L. Katz of Goodwin Procter LLP, the Company’s outside counsel, at (617) 570-1000.

Sincerely,
/s/ Michael P. Mason

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CORRESP
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CORRESP

 Alnylam Pharmaceuticals, Inc.

300 Third Street

 Cambridge, MA
02142

 January 19, 2018

 United States
Securities and Exchange Commission

 Division of Corporation Finance

100 F Street N.E.

 Washington, D.C. 20549

Attention: Frank Wyman and Jim Rosenberg, Office of Healthcare & Insurance

 RE:

Alnylam Pharmaceuticals, Inc.

Form 10-K for Fiscal Year Ended December 31, 2016

Filed February 15, 2017

File No. 001-36407

 Dear Messrs. Wyman and Rosenberg:

This letter is being furnished in response to the comments of the staff (the “Staff”) of the Securities and Exchange Commission (the
“Commission”) in the Commission’s letter dated January 8, 2018 (the “Comment Letter”) to Michael P. Mason, Vice President of Finance and Treasurer of Alnylam Pharmaceuticals, Inc. (the “Company”), with respect
to the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2016, and the documents incorporated by reference therein. The responses set forth below have been organized in the
same manner in which the Commission’s comments and headings were organized in the Comment Letter.

 Comment: Notes to the Consolidated Financial
Statements – 3. Significant Agreements, page 97

 We acknowledge the information provided in your response to our prior comment 1 of our
November 27, 2017 comment letter. As required by ASC 730-20-50-1b, please confirm to us that you will disclose herein the
costs incurred for each of your significant agreements. We would expect the amount disclosed to include the costs you provided in your response and your reasonable estimate of other costs incurred albeit for which you may not track separately for
each agreement. In this regard, it would appear that a reasonable estimate would be attainable, given that you track hours incurred for the purpose of billing your counterparties. Finally, we believe additional disclosure in your research and
development expense discussion of your MD&A of the nature and amount of research and development costs incurred related to your agreements would be informative.

Response

 In future periodic filings, including the Form 10-K for the fiscal year ended December 31, 2017, the Company will revise its disclosure to disclose the costs incurred for each of the Company’s significant agreements, including the costs provided in the
Company’s response letter dated December 11, 2017, and a reasonable estimate of other costs incurred, and the Company will include additional disclosure in the research and development expense discussion of MD&A of the nature and
amount of research and development costs incurred related to its significant agreements.

 Messrs. Frank Wyman and Jim Rosenberg

U.S. Securities and Exchange Commission

 January 19, 2018

 Page 2

 If you have any questions with regard to the Company’s responses or would like to
discuss any of the matters covered in this letter, please contact the undersigned at (617) 551-8200 or Gregg L. Katz of Goodwin Procter LLP, the Company’s outside counsel, at (617) 570-1000.

Sincerely,

/s/ Michael P. Mason

Michael P. Mason

Vice President, Finance and Treasurer