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CORRESP Filing

LIXTE BIOTECHNOLOGY HOLDINGS, INC.
Date: June 24, 2025 · CIK: 0001335105 · Accession: 0001641172-25-016281

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File numbers found in text: 333-288120

Date
June 26, 2025
Author
Chief
Form
CORRESP
Company
LIXTE BIOTECHNOLOGY HOLDINGS, INC.

Letter

RE: LIXTE BIOTECHNOLOGY HOLDINGS, INC. (CIK: 0001335105)

June 24, 2025

VIA EDGAR

Securities and Exchange Commission

Division of Corporation Finance

F Street, N.E.

Washington, DC 20549

Registration Statement No. 333-288120 on Form S-1/A (the "Registration Statement")

Ladies and Gentlemen:

Pursuant to Rule 461 of the General Rules and Regulations of the U.S. Securities and Exchange Commission under the Securities Act of 1933, as amended (the "Securities Act" ), Spartan Capital Securities, LLC hereby requests acceleration of the effective date of the above-referenced Registration Statement so that it will become effective at 5:00 p.m. Eastern Time, June 26, 2025, or as soon thereafter as practicable.

Pursuant to Rule 460 under the Securities Act, please be advised that we will distribute as many electronic copies of the proposed form of preliminary prospectus as appears to be reasonable to secure adequate distribution.

The undersigned has complied and will comply with the requirements of Rule 15c2-8 under the Securities Exchange Act of 1934, as amended.

By: SPARTAN CAPITAL SECURITIES, LLC

By:

/s/ Kim Monchik

Name: Kim Monchik

Title: Chief Administrative Officer

Show Raw Text
CORRESP
 1
 filename1.htm

 June
24, 2025

 VIA
EDGAR

 Securities
and Exchange Commission

 Division
of Corporation Finance

 100
F Street, N.E.

 Washington,
DC 20549

 RE:
 LIXTE
 BIOTECHNOLOGY HOLDINGS, INC. (CIK: 0001335105)

 Registration
 Statement No. 333-288120 on Form S-1/A (the "Registration Statement")

 Ladies
and Gentlemen:

 Pursuant
to Rule 461 of the General Rules and Regulations of the U.S. Securities and Exchange Commission under the Securities Act of 1933, as
amended (the "Securities Act" ), Spartan Capital Securities, LLC hereby requests acceleration of the effective
date of the above-referenced Registration Statement so that it will become effective at 5:00 p.m. Eastern Time, June 26, 2025, or as
soon thereafter as practicable.

 Pursuant
to Rule 460 under the Securities Act, please be advised that we will distribute as many electronic copies of the proposed form of preliminary
prospectus as appears to be reasonable to secure adequate distribution.

 The
undersigned has complied and will comply with the requirements of Rule 15c2-8 under the Securities Exchange Act of 1934, as amended.

 By:
 SPARTAN
 CAPITAL SECURITIES, LLC

 By:

 /s/
 Kim Monchik

 Name:
 Kim
 Monchik

 Title:
 Chief
 Administrative Officer