Correspondence 0001493152-23-013742 from PALISADE BIO, INC. (PALI)

PALISADE BIO, INC.
Date: April 27, 2023 · CIK: 0001357459 · Accession: 0001493152-23-013742

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File numbers found in text: 333-271393

Date

April 27, 2023

Author

Chief

Form

CORRESP

Company

PALISADE BIO, INC.

Letter

Palisade Bio, Inc.

El Camino Real, Suite 2A

Carlsbad, CA 92009

April 27, 2023

VIA EDGAR

United States Securities and Exchange Commission

Division of Corporation Finance

F. Street, N.E.

Washington, D.C. 20549

Attn: Tim Buchmiller

Re: Palisade Bio, Inc. (the “Company”)

Registration Statement on Form S-1

Originally Filed: April 21, 2023, as amended

File No.: 333-271393

Ladies and Gentlemen:

Pursuant to Rule 461 under the Securities Act of 1933, as amended, the Company hereby requests that the Securities and Exchange Commission take appropriate action to cause the above-referenced Registration Statement on Form S-1, to become effective at 5:00 pm Eastern Time on April 27, 2023, or as soon thereafter as is practicable.

If you have any questions regarding this request, please contact Dennis Gluck of Silvestre Law Group, P.C. at (818) 597-7552.

Very
truly yours,
PALISADE
BIO, INC.

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CORRESP
1
filename1.htm

Palisade
Bio, Inc.

7750
El Camino Real, Suite 2A

Carlsbad,
CA 92009

April
27, 2023

VIA
EDGAR

United
States Securities and Exchange Commission

Division
of Corporation Finance

100
F. Street, N.E.

Washington,
D.C. 20549

    Attn:
    Tim
    Buchmiller

    Re:
    Palisade
    Bio, Inc. (the “Company”)

    Registration
    Statement on Form S-1

    Originally
    Filed: April 21, 2023, as amended

    File
    No.: 333-271393

Ladies
and Gentlemen:

Pursuant
to Rule 461 under the Securities Act of 1933, as amended, the Company hereby requests that the Securities and Exchange Commission take
appropriate action to cause the above-referenced Registration Statement on Form S-1, to become effective at 5:00 pm Eastern Time on April
27, 2023, or as soon thereafter as is practicable.

If
you have any questions regarding this request, please contact Dennis Gluck of Silvestre Law Group, P.C. at (818) 597-7552.

Very
truly yours,

PALISADE
BIO, INC.

    /s/ J.D. Finley

    J.D.
    Finley

    Chief
    Executive Officer

SecProbe.io