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CORRESP
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 VIA EDGAR   September 8, 2025   United States Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549   Re: ProMIS Neurosciences Inc. Acceleration Request for Registration Statement on Form S-3 File No. 333-290039   Ladies and Gentlemen:   Pursuant to Rule 461 under the Securities Act of 1933, as amended (the “ Act ”), ProMIS Neurosciences Inc. (the “ Company ”) hereby requests that the effective date of the above-referenced registration statement (the “ Registration Statement ”) be accelerated to September 10, 2025, at 4:01 p.m., Eastern Time, or as soon thereafter as practicable, unless we or our outside counsel, Goodwin Procter LLP, request by telephone that such Registration Statement be declared effective at some other time. In making this acceleration request, the Company acknowledges that it is aware of its responsibilities under the Act.   Once the Registration Statement is effective, please orally confirm the event with our counsel, Goodwin Procter LLP by calling Adam V. Johnson at (212) 459-7072. If you have any questions regarding this request, please contact Adam V. Johnson of Goodwin Procter LLP at (212) 459-7072.   Sincerely,       PROMIS NEUROSCIENCES INC.     ​ /s/ Neil Warma   Neil Warma   Chief Executive Officer     ​ ​ ​ ​ ​ ​ cc: Adam V. Johnson, Goodwin Procter LLP