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    701
                                            Wild Rose Lane

    Elk
    City, ID 83525

    4093
    Oceanside Blvd, Suite B

    Oceanside,
    California 92056

    Ph:
    760-295-7208

    VIA
    EDGAR

    Securities
    and Exchange Commission
    February
    5, 2024

    Division
    of Corporation Finance

    100
    F Street N.E.

    Washington,
    D.C. 20549

    Attention:
    Erik
    Gerding, Director

    Colon
    Danberg, Staff Attorney

    Re:
    Therapeutic
    Solutions International, Inc. (TSOI)

    Registration
    Statement on Form S-1/A

    File
    No. 333-276559

REQUEST
FOR ACCELERATION OF EFFECTIVENESS

Dear
Mr. Gerding and Ms. Nimitz:

Pursuant
to Rule 461 promulgated under the Securities Act of 1933, as amended, Therapeutic Solutions International, Inc. (the “Registrant”)
hereby requests acceleration of the effective date of its Registration Statement on Form S-1 (File No. 333-276559), as amended (the “Registration
Statement”), so that it may become effective at 4:00 p.m. Eastern Daylight Time on February 7, 2024, or as soon as practicable
thereafter.

The
Registrant hereby authorizes Hugh D. Kelso III, Esq or H.D. Kelso & Associates, to orally modify or withdraw this request for acceleration.

The
Registrant hereby acknowledges that:

(i)
should the Securities and Exchange Commission (the “Commission”) or the staff, acting pursuant to delegated authority, declare
the Registration Statement effective, it does not foreclose the Commission from taking any action with respect to the Registration Statement;

(ii)
the action of the Commission or the staff, acting pursuant to delegated authority, in declaring the Registration Statement effective,
does not relieve the Registrant from its full responsibility for the adequacy and accuracy of the disclosure in the Registration Statement;
and

(iii)
the Registrant may not assert comments of the Commission or the staff and the declaration of effectiveness of the Registration Statement
as a defense in any proceeding initiated by the Commission or any person under the federal securities laws of the United States.

We
request that we be notified of such effectiveness by a telephone call to Mr. Kelso at (619) 840-5056. We also respectfully request that
a copy of the written order from the Commission verifying the effective time and date of such Registration Statement be sent to H.D.
Kelso & Associates, attention: Hugh Kelso, via Email at hdklawfirm@yahoo.com.

Best
Regards,

    THERAPEUTIC
    SOLUTION INTERNATIONAL, INC.

    /s/
    Timothy G. Dixon

    Timothy
    G. Dixon

    Chief
    Executive Officer

cc:
Hugh D. Kelso III, Esq.