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Correspondence 0001193125-23-133252 from Karyopharm Therapeutics Inc. (KPTI) (CIK 0001503802) (KPTI)

Karyopharm Therapeutics Inc. (KPTI) (CIK 0001503802)
Date: May 3, 2023 · CIK: 0001503802 · Accession: 0001193125-23-133252

AI Filing Summary & Sentiment

File numbers found in text: 333-269846

Date
May 3, 2023
Author
Not clearly detected
Form
CORRESP
Company
Karyopharm Therapeutics Inc. (KPTI) (CIK 0001503802)

Letter

Re: Karyopharm Therapeutics Inc.

May 3, 2023

VIA EDGAR SUBMISSION

Securities and Exchange Commission

Division of Corporation Finance

100 F Street, NE

Washington, DC 20549

Attention: Arzhang Navai

Registration Statement on Form S-3

File No. 333-269846

Request for Acceleration

Ladies and Gentlemen:

Pursuant to Rule 461 under the Securities Act of 1933, as amended, Karyopharm Therapeutics Inc. (the “Registrant”) hereby requests acceleration of the effective date of its Registration Statement on Form S-3 (File No. 333-269846), so that it may become effective at 4:30 p.m., Eastern Time, on May 5, 2023, or as soon as practicable thereafter, or at such later time as the Registrant or its counsel may orally request via telephone call to the staff.

Very truly yours,
/s/ KARYOPHARM THERAPEUTICS INC.

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CORRESP
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filename1.htm

CORRESP

 May 3, 2023

VIA EDGAR SUBMISSION

 Securities and Exchange
Commission

 Division of Corporation Finance

 100 F Street, NE

 Washington, DC 20549

 Attention:
Arzhang Navai

Re:
 Karyopharm Therapeutics Inc.

Registration Statement on Form S-3

File No. 333-269846

Request for Acceleration

 Ladies and
Gentlemen:

 Pursuant to Rule 461 under the Securities Act of 1933, as amended, Karyopharm Therapeutics Inc. (the “Registrant”) hereby requests
acceleration of the effective date of its Registration Statement on Form S-3 (File No. 333-269846), so that it may become effective at 4:30 p.m., Eastern Time,
on May 5, 2023, or as soon as practicable thereafter, or at such later time as the Registrant or its counsel may orally request via telephone call to the staff.

Very truly yours,

/s/ KARYOPHARM THERAPEUTICS INC.

By:

 /s/ Michael Mano

Name: Michael Mano

Title: Senior Vice President and General Counsel

cc:
 Jason Kropp, Wilmer Cutler Pickering Hale and Dorr LLP

Craig Hilts, Wilmer Cutler Pickering Hale and Dorr LLP