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January 25, 2024
R. Steven Hamner
Chief Financial Officer
Medical Properties Trust, Inc.
MPT Operating Partnership, L.P.
1000 Urban Center Drive, Suite 501
Birmingham, AL 35242
Re:Medical Properties Trust, Inc.
MPT Operating Partnership, L.P.
Form 10-K for the Year Ended December 31, 2021
Form 10-K for the Year Ended December 31, 2022
File No. 001-32559
Dear R. Steven Hamner:
            We issued a comment to you on the above captioned filing on January 9, 2024. As of the
date of this letter, this comment remains outstanding and unresolved. We expect you to provide a
complete, substantive response to this comment by February 8, 2024.
            If you do not respond, we will, consistent with our obligations under the federal securities
laws, decide how we will seek to resolve material outstanding comments and complete our
review of your filings and your disclosure. Among other things, we may decide to release
publicly, through the agency's EDGAR system, all correspondence, including this letter, relating
to the review of your filings, consistent with the staff's decision to publicly release comment and
response letters relating to disclosure filings it has reviewed.
            Please contact Howard Efron at 202-551-3439 or Jennifer Monick at 202-551-3295 with
any questions.
Sincerely,
Division of Corporation Finance
Office of Real Estate & Construction
cc:       Kevin Hanna