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CORRESP Filing

Can-Fite BioPharma Ltd.
Date: July 24, 2025 · CIK: 0001536196 · Accession: 0001213900-25-067307

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File numbers found in text: 333-288890

Date
July 24, 2025
Author
Motti Farbstein
Form
CORRESP
Company
Can-Fite BioPharma Ltd.

Letter

Can-Fite BioPharma Ltd.

26 Ben Gurion Street

Ramat Gan 5257346 Israel

July 24, 2025

VIA EDGAR

Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, DC 20549

RE: Can-Fite BioPharma Ltd. (CIK 0001536196)

Registration Statement No. 333-288890 on Form F-1 (the "Registration Statement")

Ladies and Gentlemen:

Can-Fite BioPharma Ltd. (the " Registrant ") hereby requests acceleration of the effectiveness of the above-referenced Registration Statement pursuant to Rule 461 under the Securities Act of 1933, as amended (the " Securities Act "), so that it may become effective on July 28, 2025 at 9:00 a.m., Eastern Time, or as soon thereafter as is practicable.

The undersigned respectfully requests that it be notified of the effectiveness of the Registration Statement by telephone call to our counsel, Greenberg Traurig, P.A., by calling Gary Emmanuel at +1 212 801 9337. The Company hereby authorizes Mr. Emmanuel to orally modify or withdraw this request for acceleration.

Very truly yours,
Can-Fite BioPharma LTD.

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CORRESP
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 Can-Fite BioPharma Ltd.

 26 Ben Gurion Street

 Ramat Gan 5257346 Israel

 July 24, 2025

 VIA EDGAR

 Securities and Exchange Commission

 Division of Corporation Finance

 100 F Street, N.E.

 Washington, DC 20549

 RE:
 Can-Fite BioPharma Ltd. (CIK 0001536196)

 Registration Statement No. 333-288890 on Form F-1 (the "Registration Statement")

 Ladies and Gentlemen:

 Can-Fite BioPharma Ltd. (the " Registrant ")
hereby requests acceleration of the effectiveness of the above-referenced Registration Statement pursuant to Rule 461 under the Securities
Act of 1933, as amended (the " Securities Act "), so that it may become effective on July 28, 2025 at 9:00 a.m., Eastern
Time, or as soon thereafter as is practicable.

 The undersigned respectfully requests
that it be notified of the effectiveness of the Registration Statement by telephone call to our counsel, Greenberg Traurig, P.A., by calling
Gary Emmanuel at +1 212 801 9337. The Company hereby authorizes Mr. Emmanuel to orally modify or withdraw this request for acceleration.

 Very truly yours,

 Can-Fite BioPharma LTD.

 By:
 /s/ Motti Farbstein

 Motti Farbstein
Chief Executive Officer and
Chief Financial Officer