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Correspondence 0001213900-25-125490 from iSpecimen Inc. (ISPC)

iSpecimen Inc.
Date: Dec. 23, 2025 · CIK: 0001558569 · Accession: 0001213900-25-125490

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File numbers found in text: 333-289725

Date
December 23, 2025
Author
/s/ Katharyn Field
Form
CORRESP
Company
iSpecimen Inc.

Letter

iSpecimen Inc.

8 Cabot Road, Suite 1800

Woburn, WA 08101

December 23, 2025

VIA EDGAR

U.S. Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

Re: iSpecimen Inc. Request for Acceleration

Registration Statement on Form S-1

File No. 333-289725

Ladies and Gentlemen:

Pursuant to Rule 461 promulgated under the Securities Act of 1933, as amended (the "Securities Act"), iSpecimen Inc., a Delaware corporation (the "Company"), respectfully requests that the effective date of its registration statement on Form S-1 (File No. 333-289725) (the "Registration Statement"), be accelerated so that it will become effective at 5:00 p.m., Eastern Time, on Monday, December 29, 2025, or as soon thereafter as possible.

Once the Registration Statement is effective, please confirm the event with our counsel, Sichenzia Ross Ference Carmel LLP by calling Ross D. Carmel, Esq. at (646) 838-1310.

If you have any questions regarding this request, please contact Ross D. Carmel, Esq. of Sichenzia Ross Ference Carmel LLP at (646) 838-1310.

Very truly yours,
By:
/s/ Katharyn Field

Show Raw Text
CORRESP
 1
 filename1.htm

 iSpecimen Inc.

 8 Cabot Road, Suite 1800

 Woburn, WA 08101

 December 23, 2025

 VIA EDGAR

 U.S. Securities and Exchange Commission

 Division of Corporation Finance

 100 F Street, N.E.

 Washington, D.C. 20549

 Re: iSpecimen Inc. Request for Acceleration

 Registration
Statement on Form S-1

 File No. 333-289725

 Ladies and Gentlemen:

 Pursuant to Rule 461 promulgated under the Securities
Act of 1933, as amended (the "Securities Act"), iSpecimen Inc., a Delaware corporation (the "Company"), respectfully
requests that the effective date of its registration statement on Form S-1 (File No. 333-289725) (the "Registration Statement"),
be accelerated so that it will become effective at 5:00 p.m., Eastern Time, on Monday, December 29, 2025, or as soon thereafter as possible.

 Once the Registration Statement is effective,
please confirm the event with our counsel, Sichenzia Ross Ference Carmel LLP by calling Ross D. Carmel, Esq. at (646) 838-1310.

 If you have any questions regarding this request,
please contact Ross D. Carmel, Esq. of Sichenzia Ross Ference Carmel LLP at (646) 838-1310.

 Very truly yours,

 By:
 /s/ Katharyn Field

 Name:
 Katharyn Field

 Title:
 Chief Executive Officer

 cc: Ross D. Carmel, Esq., Sichenzia Ross Ference Carmel LLP