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CORRESP Filing

Caribou Biosciences, Inc.
Date: May 13, 2025 · CIK: 0001619856 · Accession: 0001193125-25-119050

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File numbers found in text: 333-287093

Date
May 13, 2025
Author
Sriram Ryali
Form
CORRESP
Company
Caribou Biosciences, Inc.

Letter

Re: Caribou Biosciences, Inc. (the “Registrant”) - Request for Acceleration Registration Statement on Form S-3 File No. 333-287093 Ladies and Gentlemen: Pursuant to Rule 461 promulgated under the Securities Act of 1933, as amended, the Registrant hereby requests acceleration of the effective date of its Registration Statement on Form S-3 (File No. 333-287093) (the “Registration Statement”), so that it may become effective at 4:00 p.m. Eastern Time on Wednesday, May 14, 2025 , or as soon thereafter as practicable. The Registrant hereby authorizes each of Ashok Mukhey and Danielle Carbone of Reed Smith LLP, attorneys for the Registrant, to orally modify or withdraw this request for acceleration. The Registrant requests that it be notified of such effectiveness by a telephone call to Ashok Mukhey at (310) 734-5291 or, in his absence, Danielle Carbone at (212) 549-0229.

CARIBOU BIOSCIENCES, INC. 2929 7th Street Suite 105 Berkeley, California 94710 (510) 982-6030 May 13, 2025 VIA EDGAR United States Securities and Exchange Commission Division of Corporation Finance 100 F Street, NE Washington, D.C. 20549 Attention: Tim Buchmiller

CARIBOU BIOSCIENCES, INC.

By:

/s/ Sriram Ryali

Name: Sriram Ryali

Title: Chief Financial Officer

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CORRESP
 1
 filename1.htm

 CORRESP

 CARIBOU BIOSCIENCES, INC.
 2929 7th Street Suite
105 Berkeley, California 94710
 (510) 982-6030
 May 13, 2025 VIA EDGAR
 United States Securities and Exchange Commission
 Division of Corporation Finance 100 F Street, NE
 Washington, D.C. 20549 Attention: Tim Buchmiller

 Re:
 Caribou Biosciences, Inc. (the “Registrant”) - Request for Acceleration
 Registration Statement on Form S-3
 File No. 333-287093
 Ladies and Gentlemen: Pursuant to Rule 461
promulgated under the Securities Act of 1933, as amended, the Registrant hereby requests acceleration of the effective date of its Registration Statement on Form S-3 (File
 No. 333-287093) (the “Registration Statement”), so that it may become effective at 4:00 p.m. Eastern Time on Wednesday, May 14, 2025 , or as soon thereafter as
practicable. The Registrant hereby authorizes each of Ashok Mukhey and Danielle Carbone of Reed Smith LLP, attorneys for the Registrant,
to orally modify or withdraw this request for acceleration. The Registrant requests that it be notified of such effectiveness by a
telephone call to Ashok Mukhey at (310) 734-5291 or, in his absence, Danielle Carbone at (212) 549-0229.

 CARIBOU BIOSCIENCES, INC.

 By:

 /s/ Sriram Ryali

 Name: Sriram Ryali

 Title: Chief Financial Officer