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UPLOAD Filing

Spyre Therapeutics, Inc.
Date: June 2, 2025 · CIK: 0001636282 · Accession: 0000000000-25-005782

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File numbers found in text: 001-37722

Date
June 2, 2025
Author
Finance
Form
UPLOAD
Company
Spyre Therapeutics, Inc.

Letter

Re: Spyre Therapeutics, Inc. Form 10-K for the fiscal year ended December 31, 2024 Filed February 27, 2025 File No. 001-37722 Dear Scott Burrows:

June 2, 2025

Scott Burrows Chief Financial Officer Spyre Therapeutics, Inc. 221 Crescent Street Building 23 Suite 105 Waltham, MA 02453

We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff.

Sincerely,
Division of Corporation
Finance
Office of Life Sciences

Show Raw Text
<DOCUMENT>
<TYPE>TEXT-EXTRACT
<SEQUENCE>2
<FILENAME>filename2.txt
<TEXT>
 June 2, 2025

Scott Burrows
Chief Financial Officer
Spyre Therapeutics, Inc.
221 Crescent Street
Building 23
Suite 105
Waltham, MA 02453

 Re: Spyre Therapeutics, Inc.
 Form 10-K for the fiscal year ended December 31, 2024
 Filed February 27, 2025
 File No. 001-37722
Dear Scott Burrows:

 We have completed our review of your filing. We remind you that the
company and
its management are responsible for the accuracy and adequacy of their
disclosures,
notwithstanding any review, comments, action or absence of action by the staff.

 Sincerely,

 Division of Corporation
Finance
 Office of Life Sciences
</TEXT>
</DOCUMENT>