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Correspondence 0001193125-26-129018 from Cue Biopharma, Inc. (CUE)

Cue Biopharma, Inc.
Date: March 27, 2026 · CIK: 0001645460 · Accession: 0001193125-26-129018

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File numbers found in text: 333-294366

Date
March 27, 2026
Author
Lucinda Warren
Form
CORRESP
Company
Cue Biopharma, Inc.

Letter

Re: Cue Biopharma, Inc. Registration Statement on Form S-3 Filed March 16, 2026 File No. 333-294366 Request for Acceleration Ladies and Gentlemen: Pursuant to Rule 461 under the Securities Act of 1933, as amended, Cue Biopharma, Inc. (the “ Registrant ”) hereby requests acceleration of the effective date of its Registration Statement on Form S-3 (File No. 333-294366), so that it may become effective at 4:00 p.m. Eastern time on March 31, 2026, or as soon thereafter as practicable, or at such later time as the Registrant or its counsel may orally request via telephone call to the Staff.

CUE BIOPHARMA, INC. 40 Guest Street Boston, Massachusetts 02135 March 27, 2026 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance, Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549 Attention: Tim Buchmiller

Very truly yours,
CUE BIOPHARMA, INC.

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CORRESP
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 CORRESP

 CUE BIOPHARMA, INC.
 40 Guest Street Boston,
Massachusetts 02135 March 27, 2026 VIA EDGAR
 U.S. Securities and Exchange Commission Division of
Corporation Finance, Office of Life Sciences 100 F Street, N.E.
 Washington, D.C. 20549 Attention: Tim Buchmiller

 Re:
 Cue Biopharma, Inc.
 Registration Statement on Form S-3
 Filed March 16, 2026 File No. 333-294366 Request for Acceleration
 Ladies and Gentlemen: Pursuant to Rule 461
under the Securities Act of 1933, as amended, Cue Biopharma, Inc. (the “ Registrant ”) hereby requests acceleration of the effective date of its Registration Statement on Form S-3 (File No. 333-294366), so that it may become effective at 4:00 p.m. Eastern time on March 31, 2026, or as soon thereafter as practicable, or at such later time as the Registrant or its counsel may orally request
via telephone call to the Staff.

 Very truly yours,

 CUE BIOPHARMA, INC.

 By:

 /s/ Lucinda Warren

 Name:

 Lucinda Warren

 Title:

 Interim President and Chief Executive Officer