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Correspondence 0001193125-26-271175 from Cue Biopharma, Inc. (CUE)

Cue Biopharma, Inc.
Date: June 15, 2026 · CIK: 0001645460 · Accession: 0001193125-26-271175

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File numbers found in text: 333-296456

Date
June 15, 2026
Author
Sumita Ray
Form
CORRESP
Company
Cue Biopharma, Inc.

Letter

Re: Cue Biopharma, Inc. Registration Statement on Form S-3 (File No. 333-296456) Request for Acceleration of Effective Date Chris Edwards: In accordance with Rule 461 under the Securities Act of 1933, as amended, the undersigned registrant (the “ Registrant ”) hereby requests that the Securities and Exchange Commission (the “ Commission ”) take appropriate action to cause the above-referenced Registration Statement on Form S-3 (File No. 333-296456) (the “ Registration Statement ”) to become effective on June 17, 2026, at 4:00 p.m. Eastern Time, or as soon thereafter as is practicable, or at such other time as the Registrant or its legal counsel, Cooley LLP, may request by telephone to the staff of the Commission. The Registrant hereby authorizes each of Courtney M.W. Tygesson and Sara Semnani of Cooley LLP to make such a request on its behalf. Once the Registration Statement has been declared effective, please confirm that event with Courtney M.W. Tygesson of Cooley LLP, counsel to the Registrant, at (312) 881-6680 or ctygesson@cooley.com, or in her absence, Sara Semnani at (858) 550-6227or ssemnani@cooley.com. [Signature page follows]

C UE B IOPHARMA , I NC . 40 Guest Street Boston, Massachusetts 02135 June 15, 2026 Via EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Attn: Chris Edwards

Very truly yours,
Cue Biopharma, Inc.

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CORRESP
 1
 filename1.htm

 CORRESP

 C UE B IOPHARMA , I NC .
 40 Guest Street Boston,
Massachusetts 02135 June 15, 2026 Via
EDGAR U.S. Securities and Exchange Commission Division of
Corporation Finance 100 F Street, N.E. Washington, D.C.
20549 Attn: Chris Edwards

 Re:
 Cue Biopharma, Inc.
 Registration Statement on Form S-3 (File
 No. 333-296456) Request for Acceleration of Effective Date
 Chris Edwards: In accordance with Rule 461 under the Securities
Act of 1933, as amended, the undersigned registrant (the “ Registrant ”) hereby requests that the Securities and Exchange Commission (the “ Commission ”) take appropriate action to cause the
above-referenced Registration Statement on Form S-3 (File No. 333-296456) (the “ Registration Statement ”) to become effective on
June 17, 2026, at 4:00 p.m. Eastern Time, or as soon thereafter as is practicable, or at such other time as the Registrant or its legal counsel, Cooley LLP, may request by telephone to the staff of the Commission. The Registrant hereby
authorizes each of Courtney M.W. Tygesson and Sara Semnani of Cooley LLP to make such a request on its behalf. Once the Registration Statement has been
declared effective, please confirm that event with Courtney M.W. Tygesson of Cooley LLP, counsel to the Registrant, at (312) 881-6680 or ctygesson@cooley.com, or in her absence, Sara Semnani at (858) 550-6227or ssemnani@cooley.com. [Signature page follows]

 Very truly yours,

 Cue Biopharma, Inc.

 By:

 /s/ Sumita Ray

 Sumita Ray

 Chief Legal & Compliance Officer and Corporate Secretary

 cc:
 Shao-Lee Lin, Cue Biopharma, Inc.
 Michael Meluzio, Cue Biopharma, Inc.
 Divakar Gupta, Cooley LLP Sara
Semnani, Cooley LLP Courtney M.W. Tygesson, Cooley LLP
 Signature Page to
Company Acceleration Request – S-3