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CORRESP Filing

Aptevo Therapeutics Inc.
Date: Nov. 24, 2025 · CIK: 0001671584 · Accession: 0001193125-25-293460

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File numbers found in text: 333-290663

Date
November 24, 2025
Author
Marvin L. White
Form
CORRESP
Company
Aptevo Therapeutics Inc.

Letter

November 24, 2025 VIA EDGAR United States Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549 Attention: Chris Edwards Re: Aptevo Therapeutics Inc. Registration Statement on Form S-1 Filed October 1, 2025 File No. 333-290663 Dear Mr. Edwards: In accordance with Rule 461 under the Securities Act of 1933, as amended, we hereby request acceleration of the effective date of the Registration Statement on Form S-1 (File No. 333-290663) of Aptevo Therapeutics Inc. (the “Registration Statement”). We respectfully request that the Registration Statement become effective as of 4:00 p.m., Eastern Time, on November 25, 2025, or as soon as practicable thereafter. Once the Registration Statement has been declared effective, please confirm that event with our counsel, Paul Hastings LLP, by calling Sean M. Donahue at (202) 551-1704. Very truly yours, Aptevo Therapeutics Inc. By: /s/ Marvin L. White Marvin L. White President and Chief Executive Officer

CC: SoYoung Kwon, Aptevo Therapeutics Inc. Daphne Taylor, Aptevo Therapeutics Inc. Sean M. Donahue, Paul Hastings LLP

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CORRESP
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 CORRESP

 November 24, 2025 VIA EDGAR United States Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549 Attention: Chris Edwards Re: Aptevo Therapeutics Inc. Registration Statement on Form S-1 Filed October 1, 2025 File No. 333-290663 Dear Mr. Edwards: In accordance with Rule 461 under the Securities Act of 1933, as amended, we hereby request acceleration of the effective date of the Registration Statement on Form S-1 (File No. 333-290663) of Aptevo Therapeutics Inc. (the “Registration Statement”). We respectfully request that the Registration Statement become effective as of 4:00 p.m., Eastern Time, on November 25, 2025, or as soon as practicable thereafter. Once the Registration Statement has been declared effective, please confirm that event with our counsel, Paul Hastings LLP, by calling Sean M. Donahue at (202) 551-1704. Very truly yours, Aptevo Therapeutics Inc. By: /s/ Marvin L. White Marvin L. White President and Chief Executive Officer

 CC:
 SoYoung Kwon, Aptevo Therapeutics Inc. Daphne Taylor, Aptevo Therapeutics Inc. Sean M. Donahue, Paul Hastings LLP