CORRESP Filing
HYPERION DEFI, INC.
Date: Dec. 8, 2025 · CIK: 0001682639 · Accession: 0001104659-25-119131
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File numbers found in text: 333-291570
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CORRESP 1 filename1.htm December 8, 2025 Via EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Attn: Jimmy MacNamara Re: Hyperion DeFi, Inc. (the "Company") Registration Statement Filed on Form S-3 (the "Registration Statement") File No. 333-291570 Ladies and Gentlemen: Pursuant to Rule 461 under the Securities Act of 1933, as amended, the Company hereby respectfully requests that the effective date for the above-referenced Registration Statement be accelerated to 8:00 a.m., Eastern Time, on December 9, 2025, or as soon as practicable thereafter. Please contact Megan Gates of Covington & Burling LLP at (617) 785-4653 or mgates@cov.com with any questions you may have regarding this request. In addition, please notify Ms. Gates by telephone when this request for acceleration has been granted. Respectfully, Hyperion DeFi, Inc. By: /s/ Hyunsu Jung Name: Hyunsu Jung Title: Interim Chief Executive Officer cc: Megan Gates, Covington & Burling LLP