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Correspondence 0001213900-25-010170 from 180 Life Sciences Corp. (ATNF, ATNFW) (CIK 0001690080) (ETHZ)

180 Life Sciences Corp. (ATNF, ATNFW) (CIK 0001690080)
Date: Feb. 4, 2025 · CIK: 0001690080 · Accession: 0001213900-25-010170

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File numbers found in text: 333-283265

Date
February 4, 2025
Author
/s/ Blair Jordan
Form
CORRESP
Company
180 Life Sciences Corp. (ATNF, ATNFW) (CIK 0001690080)

Letter

180 LIFE SCIENCES CORP.

3000 El Camino Real

Bldg. 4, Suite 200

Palo Alto, CA 94306

February 4, 2025

Division of Corporation Finance VIA EDGAR

U.S. Securities and Exchange Commission

Washington D.C. 20549

Re: 180 Life Sciences Corp.

Form S-1 Registration Statement

File No. 333-283265

Acceleration Request

Request Date: February 7, 2025

Request Time: 4:00 p.m. Eastern Time (or as soon thereafter as practicable)

Ladies and Gentlemen:

Pursuant to Rule 461 under the Securities Act of 1933, as amended, 180 Life Sciences Corp. (the “Registrant”) hereby requests that the United States Securities and Exchange Commission (the “Commission”) take appropriate action to cause the above-captioned Registration Statement (the “Registration Statement”) to become effective at 4:00 p.m. Eastern Standard Time, Friday, February 7, 2025, or as soon thereafter as practicable.

Please contact Mr. David M. Loev of The Loev Law Firm, PC at (832) 930-6432, with any questions you may have concerning this request, and please notify him when this request for acceleration has been granted.

Very truly yours,
/s/ Blair Jordan

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CORRESP
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180 LIFE SCIENCES CORP.

3000 El Camino Real

Bldg. 4, Suite 200

Palo Alto, CA 94306

February 4, 2025

    Division of Corporation Finance
    VIA EDGAR

U.S. Securities and Exchange Commission

Washington D.C. 20549

 Re: 180 Life Sciences Corp.

Form S-1 Registration Statement

File No. 333-283265

Acceleration Request

Request Date: February 7, 2025

Request Time: 4:00 p.m. Eastern Time (or
as soon thereafter as practicable)

Ladies and Gentlemen:

Pursuant to Rule 461 under
the Securities Act of 1933, as amended, 180 Life Sciences Corp. (the “Registrant”) hereby requests that the
United States Securities and Exchange Commission (the “Commission”) take appropriate action to cause the above-captioned
Registration Statement (the “Registration Statement”) to become effective at 4:00 p.m. Eastern Standard Time, Friday,
February 7, 2025, or as soon thereafter as practicable.

Please contact Mr. David M.
Loev of The Loev Law Firm, PC at (832) 930-6432, with any questions you may have concerning this request, and please notify him when this
request for acceleration has been granted.

    Very truly yours,

    /s/ Blair Jordan

    Blair Jordan

    Interim Chief Executive Officer