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CORRESP Filing

Equillium, Inc. (EQ) (CIK 0001746466)
Date: March 23, 2026 · CIK: 0001746466 · Accession: 0001193125-26-120364

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File numbers found in text: 333-291510

Date
March 23, 2026
Author
Bruce D. Steel
Form
CORRESP
Company
Equillium, Inc. (EQ) (CIK 0001746466)

Letter

Re: Equillium, Inc. Registration Statement on Form S-3 Filed: November 13, 2025 File No. 333-291510 Ladies and Gentlemen: Equillium, Inc. (the “ Registrant ”) hereby requests that the U.S. Securities and Exchange Commission (the “ Commission ”) take appropriate action to cause the above-referenced Registration Statement on Form S-3 to become effective on March 25, 2026, at 4:01 p.m., Eastern Time, or as soon thereafter as is practicable or at such later time as the Registrant may orally request via telephone call to the staff of the Commission. The Registrant hereby authorizes Dylan Kornbluth of Cooley LLP, counsel to the Registrant, to make such request on its behalf. Once the Registration Statement has been declared effective, please orally confirm that event with Dylan Kornbluth of Cooley LLP at (858) 550-6173. [ Signature Page Follows ]

E QUILLIUM , I NC . 2223 Avenida de la Playa, Suite 105 La Jolla, California 92037 March 23, 2026 Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F. Street N.E. Washington, D.C. 20549-3010 Attention: Kevin Vaughn

Very truly yours,
EQUILLIUM, INC.

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CORRESP
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 filename1.htm

 CORRESP

 E QUILLIUM , I NC .
 2223 Avenida de la Playa, Suite 105
 La Jolla, California 92037 March 23, 2026
 Securities and Exchange Commission Division of Corporation
Finance Office of Life Sciences 100 F. Street N.E.
 Washington, D.C. 20549-3010 Attention: Kevin Vaughn

 Re:
 Equillium, Inc.
 Registration Statement on Form S-3
 Filed: November 13, 2025
 File No. 333-291510
 Ladies and Gentlemen: Equillium, Inc. (the
“ Registrant ”) hereby requests that the U.S. Securities and Exchange Commission (the “ Commission ”) take appropriate action to cause the above-referenced Registration Statement on Form S-3 to become effective on March 25, 2026, at 4:01 p.m., Eastern Time, or as soon thereafter as is practicable or at such later time as the Registrant may orally request via telephone call to the staff of the
Commission. The Registrant hereby authorizes Dylan Kornbluth of Cooley LLP, counsel to the Registrant, to make such request on its behalf. Once the
Registration Statement has been declared effective, please orally confirm that event with Dylan Kornbluth of Cooley LLP at (858) 550-6173.
 [ Signature Page Follows ]

 Very truly yours,

 EQUILLIUM, INC.

 By:

 /s/ Bruce D. Steel

 Name: Bruce D. Steel

 Title: Chief Executive Officer

 cc:
 Penny Tom, Equillium, Inc.
 Thomas A. Coll, Esq., Cooley LLP
 Dylan S. Kornbluth, Esq., Cooley LLP
 [C OMPANY S IGNATURE P AGE TO E FFECTIVENESS R EQUEST ]