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CORRESP Filing

Cabaletta Bio, Inc.
Date: Aug. 13, 2025 · CIK: 0001759138 · Accession: 0001193125-25-179840

Offering / Registration Process

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File numbers found in text: 333-289339

Date
August 7, 2025
Author
Steven Nichtberger, M.D.
Form
CORRESP
Company
Cabaletta Bio, Inc.

Letter

Re: Cabaletta Bio, Inc.: Registration Statement on Form S-3 filed August 7, 2025 (File No. 333-289339) Ladies and Gentlemen: Pursuant to Rule 461 under the Securities Act of 1933, as amended (the “ Act ”), Cabaletta Bio, Inc. (the “ Company ”) hereby requests that the effective date of the above-referenced registration statement (the “ Registration Statement ”) be accelerated to August 15, 2025, at 4:01 pm Eastern Time, or as soon thereafter as practicable, unless we or our outside counsel, Goodwin Procter LLP, request by telephone that such Registration Statement be declared effective at some other time. In making this acceleration request, the Company acknowledges that it is aware of its responsibilities under the Act. If you have any questions regarding this request, please contact Finnbarr Murphy, Esq. of Goodwin Procter LLP at (212) 459-7257.

Cabaletta Bio, Inc. 2929 Arch Street, Suite 600 Philadelphia, Pennsylvania 19104 August 13, 2025 Via EDGAR Transmission Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Attention: Joshua Gorsky

Sincerely,
CABALETTA BIO, INC.

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CORRESP
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 CORRESP

 Cabaletta Bio, Inc.
 2929 Arch Street, Suite 600
 Philadelphia, Pennsylvania 19104 August 13,
2025 Via EDGAR Transmission Securities and
Exchange Commission Division of Corporation Finance 100 F
Street, N.E. Washington, D.C. 20549 Attention: Joshua
Gorsky

 Re:
 Cabaletta Bio, Inc.: Registration Statement on Form S-3 filed
August 7, 2025 (File No. 333-289339)
 Ladies and Gentlemen: Pursuant to Rule 461 under the
Securities Act of 1933, as amended (the “ Act ”), Cabaletta Bio, Inc. (the “ Company ”) hereby requests that the effective date of the above-referenced registration statement (the “ Registration
Statement ”) be accelerated to August 15, 2025, at 4:01 pm Eastern Time, or as soon thereafter as practicable, unless we or our outside counsel, Goodwin Procter LLP, request by telephone that such Registration Statement be declared
effective at some other time. In making this acceleration request, the Company acknowledges that it is aware of its responsibilities under the Act. If
you have any questions regarding this request, please contact Finnbarr Murphy, Esq. of Goodwin Procter LLP at (212) 459-7257.

 Sincerely,

 CABALETTA BIO, INC.

 /s/ Steven Nichtberger, M.D.

 Steven Nichtberger, M.D. President and Chief
Executive Officer

 cc:
 Michael Gerard, Esq., Cabaletta Bio, Inc.
 Mitchell S. Bloom, Esq., Goodwin Procter LLP
 Finnbarr Murphy, Esq., Goodwin Procter LLP