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Correspondence 0001104659-24-008852 from Aprea Therapeutics, Inc. (APRE)

Aprea Therapeutics, Inc.
Date: Jan. 31, 2024 · CIK: 0001781983 · Accession: 0001104659-24-008852

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File numbers found in text: 333-276702

Date
January 31, 2024
Author
Oren Gilad, Ph.D.
Form
CORRESP
Company
Aprea Therapeutics, Inc.

Letter

VIA EDGAR United States Securities and Exchange Commission Division of Corporation Finance Attention: Chris Edwards Registration Statement on Form S-3 Filed January 26, 2024 File No. 333-276702 Acceleration Request

Dear Mr. Edwards:

With respect to the above-referenced Registration Statement on Form S-3 (the “Registration Statement”), and pursuant to Rule 461 of Regulation C promulgated under the Securities Act of 1933, as amended, the undersigned hereby respectfully requests, on behalf of Aprea Therapeutics, Inc. (the “Company”), that the Securities and Exchange Commission (the “Commission”) accelerate the effective date of the Registration Statement to Friday, February 2, 2024, at 4:00 p.m. Eastern Time, or as soon as practicable thereafter, unless we or our outside counsel, DLA Piper LLP (US), request by telephone that such Registration Statement be declared effective at some other time.

The cooperation of the staff in meeting the timetable described above is very much appreciated.

Please call Fahd Riaz of DLA Piper LLP (US), counsel to the Company, at (215) 656-3316, with any comments or questions regarding the Registration Statement.

Very truly yours,
Aprea Therapeutics, Inc.

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CORRESP
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filename1.htm

Aprea Therapeutics,
Inc.

3805 Old Easton Road

Doylestown, PA 18902

January 31, 2024

VIA EDGAR

United States Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

Attention: Chris Edwards

    RE:
    Aprea Therapeutics,
Inc.

    Registration Statement on Form S-3

    Filed January 26, 2024

    File No. 333-276702

    Acceleration Request

Dear Mr. Edwards:

With respect to the above-referenced
Registration Statement on Form S-3 (the “Registration Statement”), and pursuant to Rule 461 of Regulation C promulgated
under the Securities Act of 1933, as amended, the undersigned hereby respectfully requests, on behalf of Aprea Therapeutics, Inc.
(the “Company”), that the Securities and Exchange Commission (the “Commission”) accelerate the effective date
of the Registration Statement to Friday, February 2, 2024, at 4:00 p.m. Eastern Time, or as soon as practicable thereafter, unless we
or our outside counsel, DLA Piper LLP (US), request by telephone that such Registration Statement be declared effective at some other
time.

The cooperation of the
staff in meeting the timetable described above is very much appreciated.

Please call Fahd Riaz
of DLA Piper LLP (US), counsel to the Company, at (215) 656-3316, with any comments or questions regarding the Registration Statement.

    Very truly yours,

    Aprea Therapeutics, Inc.

    /s/ Oren Gilad

    Oren Gilad, Ph.D.

    Chief Executive Officer

    cc:
    Patrick O’Malley, Esq., DLA Piper LLP (US)

Dylan Caplan, Esq., DLA
Piper LLP (US)