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Correspondence 0001104659-24-051633 from Aprea Therapeutics, Inc. (APRE)

Aprea Therapeutics, Inc.
Date: April 25, 2024 · CIK: 0001781983 · Accession: 0001104659-24-051633

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File numbers found in text: 333-278485

Date
April 25, 2024
Author
Oren Gilad
Form
CORRESP
Company
Aprea Therapeutics, Inc.

Letter

APREA THERAPEUTICS, INC.

3805 Old Easton Road

Doylestown, PA 18902

April 25, 2024

VIA EDGAR

Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

Attention: Chris Edwards

Re: Aprea Therapeutics, Inc.

Registration Statement on Form S-3

File No. 333-278485

Request for Acceleration

Ladies and Gentlemen:

Pursuant to Rule 461 promulgated under the Securities Act of 1933, as amended, Aprea Therapeutics, Inc. (the “Registrant”) hereby requests acceleration of the effective date of its Registration Statement on Form S-3 (File No. 333-278485), so that it may become effective at 4:30 p.m. Eastern Time on April 29, 2024, or as soon as practicable thereafter, or at such later time as the Registrant or its counsel may orally request via telephone call to the staff.

The cooperation of the staff in meeting the timetable described above is very much appreciated.

Please call Fahd Riaz, Esq. of DLA Piper LLP (US), counsel to the Company, at (215) 656-3316, with any comments or questions regarding the Registration Statement.

Very truly yours,
APREA THERAPEUTICS, INC.

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CORRESP
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APREA THERAPEUTICS, INC.

3805 Old Easton Road

Doylestown, PA 18902

April 25, 2024

VIA EDGAR

Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

Attention: Chris Edwards

    Re:
    Aprea Therapeutics, Inc.

    Registration Statement on Form S-3

    File No. 333-278485

    Request for Acceleration

Ladies and Gentlemen:

Pursuant
to Rule 461 promulgated under the Securities Act of 1933, as amended, Aprea Therapeutics, Inc. (the “Registrant”)
hereby requests acceleration of the effective date of its Registration Statement on Form S-3 (File No. 333-278485), so
that it may become effective at 4:30 p.m. Eastern Time on April 29, 2024, or as soon as practicable thereafter, or at such later
time as the Registrant or its counsel may orally request via telephone call to the staff.

The
cooperation of the staff in meeting the timetable described above is very much appreciated.

Please
call Fahd Riaz, Esq. of DLA Piper LLP (US), counsel to the Company, at (215) 656-3316, with any comments or questions regarding
the Registration Statement.

    Very truly yours,

    APREA THERAPEUTICS, INC.

    By:
    /s/ Oren Gilad           

    Name:
    Oren Gilad                            

    Title:
    Chief Executive Officer

    cc:
    Patrick O’Malley, Esq., DLA Piper LLP (US)

    Dylan Caplan, Esq., DLA Piper LLP (US)