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CORRESP Filing

Tango Therapeutics, Inc.
Date: Dec. 8, 2025 · CIK: 0001819133 · Accession: 0001193125-25-311209

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File numbers found in text: 333-291683

Date
December 8, 2025
Author
/s/ Barbara Weber
Form
CORRESP
Company
Tango Therapeutics, Inc.

Letter

VIA EDGAR December 8, 2025 United States Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549 Attention: Jimmy McNamara Re: Tango Therapeutics, Inc. Acceleration Request for Registration Statement on Form S-3 File No. 333-291683 Dear Mr. McNamara, Pursuant to Rule 461 under the Securities Act of 1933, as amended (the “ Act ”), Tango Therapeutics, Inc. (the “ Company ”) hereby requests that the effective date of the above-referenced registration statement (the “ Registration Statement ”) be accelerated to December 10, 2025, at 4:01 p.m., Eastern Time, or as soon thereafter as practicable, unless we or our outside counsel, Goodwin Procter LLP, request by telephone that such Registration Statement be declared effective at some other time. In making this acceleration request, the Company acknowledges that it is aware of its responsibilities under the Act. Once the Registration Statement is effective, please orally confirm the event with our counsel, Goodwin Procter LLP by calling Sarah Ashfaq at (212) 459-7238. If you have any questions regarding this request, please contact Sarah Ashfaq of Goodwin Procter LLP at (212) 459-7238.

Sincerely,
TANGO THERAPEUTICS, INC.

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CORRESP
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 filename1.htm

 CORRESP

 VIA EDGAR
 December 8, 2025 United States Securities and Exchange
Commission Division of Corporation Finance Office of Life
Sciences 100 F Street, N.E. Washington, D.C. 20549
 Attention: Jimmy McNamara Re: Tango Therapeutics, Inc.
 Acceleration Request for Registration Statement on Form S-3
 File No. 333-291683
 Dear Mr. McNamara, Pursuant to Rule 461 under the Securities
Act of 1933, as amended (the “ Act ”), Tango Therapeutics, Inc. (the “ Company ”) hereby requests that the effective date of the above-referenced registration statement (the “ Registration
Statement ”) be accelerated to December 10, 2025, at 4:01 p.m., Eastern Time, or as soon thereafter as practicable, unless we or our outside counsel, Goodwin Procter LLP, request by telephone that such Registration Statement be
declared effective at some other time. In making this acceleration request, the Company acknowledges that it is aware of its responsibilities under the Act.
 Once the Registration Statement is effective, please orally confirm the event with our counsel, Goodwin Procter LLP by calling Sarah Ashfaq at (212) 459-7238. If you have any questions regarding this request, please contact Sarah Ashfaq of Goodwin Procter LLP at (212) 459-7238.

 Sincerely,

 TANGO THERAPEUTICS, INC.

 /s/ Barbara Weber

 Barbara Weber

 Chief Executive Officer and President

 cc:
 Daniella Beckman, Tango Therapeutics, Inc.
 Julie Fogarty, Tango Therapeutics, Inc.
 Mitchell S. Bloom, Esq., Goodwin Procter LLP