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SEC Comment Letter for Scilex Holding (SCLX) — Dec 4, 2025

Scilex Holding Co
Date: Dec. 4, 2025 · CIK: 0001820190 · Accession: 0000000000-25-011265

Financial Reporting Regulatory Compliance

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File numbers found in text: 001-39852

Date
December 4, 2025
Author
Stephen Ma
Form
UPLOAD
Company
Scilex Holding Co

Letter

December 4, 2025 Stephen Ma Chief Financial Officer Scilex Holding Company 960 San Antonio Road Palo Alto, California 94303 Re:Scilex Holding Company Form 10-K for the Fiscal Year Ended December 31, 2024 Filed March 31, 2025 File No. 001-39852 Dear Stephen Ma: We have completed our review of your filings. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Life Sciences

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December 4, 2025
Stephen Ma
Chief Financial Officer
Scilex Holding Company
960 San Antonio Road
Palo Alto, California 94303
Re:Scilex Holding Company
Form 10-K for the Fiscal Year Ended December 31, 2024
Filed March 31, 2025
File No. 001-39852
Dear Stephen Ma:
            We have completed our review of your filings. We remind you that the company and
its management are responsible for the accuracy and adequacy of their disclosures,
notwithstanding any review, comments, action or absence of action by the staff.
Sincerely,
Division of Corporation Finance
Office of Life Sciences