CORRESP Filing
Clene Inc.
Date: Sept. 10, 2025 · CIK: 0001822791 · Accession: 0001437749-25-028735
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File numbers found in text: 333-290075
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CORRESP 1 filename1.htm clnn20250910_corresp.htm Clene Inc. 6550 South Millrock Drive, Suite G50 Salt Lake City, Utah 84121 VIA EDGAR September 10, 2025 U.S. Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549 Attention: Chris Edwards Re: Clene Inc. Acceleration Request for Registration Statement on Form S-3 File No. 333-290075 Ladies and Gentlemen: Pursuant to Rule 461 under the Securities Act of 1933, as amended (the “Act”), Clene Inc. (the “Company”) hereby requests acceleration of the effective date of the above referenced registration statement (the “Registration Statement”) to 4:00 p.m., Eastern Time, on September 12, 2025, or as soon thereafter as practicable. Please contact Tom McAleavey of Holland & Knight, special counsel to the Company, by email at tom.mcaleavey@hklaw.com or by phone at (407) 244-5108 if you have any other questions or concerns regarding this matter. [Signature Page Follows] Sincerely, /s/ Robert Etherington Name: Robert Etherington Title: President and Chief Executive Officer