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CORRESP Filing

GRI Bio, Inc.
Date: Dec. 9, 2025 · CIK: 0001824293 · Accession: 0001628280-25-056216

Offering / Registration Process

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File numbers found in text: 333-291999

Date
December 9, 2025
Author
W. Marc Hertz, Ph.D.
Form
CORRESP
Company
GRI Bio, Inc.

Letter

Document GRI BIO, INC. 2223 AVENIDA DE LA PLAYA, SUITE 208 LA JOLLA, CA 92037 VIA EDGAR December 9, 2025 U.S. Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549 Attn: Doris Stacey Gama Re: GRI Bio, Inc. Registration Statement on Form S-1, as amended (File No. 333-291999) Request for Acceleration of Effective Date Ladies and Gentlemen: Pursuant to Rule 461 under the Securities Act of 1933, as amended, GRI Bio, Inc. (the “ Company ”) hereby requests that the Securities and Exchange Commission (the “ Commission ”) accelerate the effective date of the above-referenced Registration Statement on Form S-1 (the “ Registration Statement ”) so that the Registration Statement will be declared effective as of 5:15 p.m. Eastern Time, on December 10, 2025, or as soon as practicable thereafter. The Company hereby authorizes Melanie Ruthrauff Levy, an attorney at the Company’s outside legal counsel, Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C., to orally modify or withdraw this request for acceleration. Once the Registration Statement has been declared effective, please orally confirm that event with Ms. Levy at (858) 314-1873. Thank you for your assistance in this matter. Very truly yours, GRI BIO, INC. /s/ W. Marc Hertz, Ph.D. W. Marc Hertz, Ph.D. Chief Executive Officer cc: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C. Adam Lenain, Esq. Melanie Ruthrauff Levy, Esq.

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CORRESP
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 Document GRI BIO, INC. 2223 AVENIDA DE LA PLAYA, SUITE 208 LA JOLLA, CA 92037 VIA EDGAR December 9, 2025 U.S. Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549 Attn: Doris Stacey Gama Re: GRI Bio, Inc. Registration Statement on Form S-1, as amended (File No. 333-291999) Request for Acceleration of Effective Date Ladies and Gentlemen: Pursuant to Rule 461 under the Securities Act of 1933, as amended, GRI Bio, Inc. (the “ Company ”) hereby requests that the Securities and Exchange Commission (the “ Commission ”) accelerate the effective date of the above-referenced Registration Statement on Form S-1 (the “ Registration Statement ”) so that the Registration Statement will be declared effective as of 5:15 p.m. Eastern Time, on December 10, 2025, or as soon as practicable thereafter. The Company hereby authorizes Melanie Ruthrauff Levy, an attorney at the Company’s outside legal counsel, Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C., to orally modify or withdraw this request for acceleration. Once the Registration Statement has been declared effective, please orally confirm that event with Ms. Levy at (858) 314-1873. Thank you for your assistance in this matter. Very truly yours, GRI BIO, INC. /s/ W. Marc Hertz, Ph.D. W. Marc Hertz, Ph.D. Chief Executive Officer cc: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C. Adam Lenain, Esq. Melanie Ruthrauff Levy, Esq.