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Correspondence 0001193125-25-065485 from Monte Rosa Therapeutics, Inc. (GLUE)

Monte Rosa Therapeutics, Inc.
Date: March 27, 2025 · CIK: 0001826457 · Accession: 0001193125-25-065485

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File numbers found in text: 333-285942

Date
March 27, 2025
Author
/s/ Markus Warmuth
Form
CORRESP
Company
Monte Rosa Therapeutics, Inc.

Letter

Re: Monte Rosa Therapeutics, Inc.: Registration Statement on Form S-3 filed March 20, 2025 (File No. 333-285942) Ladies and Gentlemen: Pursuant to Rule 461 under the Securities Act of 1933, as amended (the “ Act ”), Monte Rosa Therapeutics, Inc. (the “ Company ”) hereby requests that the effective date of the above-referenced registration statement (the “ Registration Statement ”) be accelerated to March 31, 2025, at 4:01 pm Eastern Time, or as soon thereafter as practicable, unless we or our outside counsel, Goodwin Procter LLP, request by telephone that such Registration Statement be declared effective at some other time. In making this acceleration request, the Company acknowledges that it is aware of its responsibilities under the Act. If you have any questions regarding this request, please contact Robert Puopolo, Esq. of Goodwin Procter LLP at (617) 570-1393.

Monte Rosa Therapeutics, Inc. 321 Harrison Avenue, Suite 900 Boston, MA 02118 March 27, 2025 Via EDGAR Transmission Securities and Exchange Commission Office of Life Sciences Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Attention: Tyler Howes

Sincerely,
MONTE ROSA THERAPEUTICS, INC.

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CORRESP
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 CORRESP

 Monte Rosa Therapeutics, Inc.
 321 Harrison Avenue, Suite 900
 Boston, MA 02118 March 27, 2025
 Via EDGAR Transmission Securities and Exchange
Commission Office of Life Sciences Division of Corporation Finance
 100 F Street, N.E. Washington, D.C. 20549
 Attention: Tyler Howes

 Re:
 Monte Rosa Therapeutics, Inc.: Registration Statement on Form S-3 filed
March 20, 2025 (File No. 333-285942)
 Ladies and Gentlemen: Pursuant to Rule 461
under the Securities Act of 1933, as amended (the “ Act ”), Monte Rosa Therapeutics, Inc. (the “ Company ”) hereby requests that the effective date of the above-referenced registration statement (the
“ Registration Statement ”) be accelerated to March 31, 2025, at 4:01 pm Eastern Time, or as soon thereafter as practicable, unless we or our outside counsel, Goodwin Procter LLP, request by telephone that such Registration
Statement be declared effective at some other time. In making this acceleration request, the Company acknowledges that it is aware of its responsibilities under the Act.
 If you have any questions regarding this request, please contact Robert Puopolo, Esq. of Goodwin Procter LLP at
 (617) 570-1393.

 Sincerely,

 MONTE ROSA THERAPEUTICS, INC.

 /s/ Markus Warmuth

 Markus Warmuth, M.D. President and Chief
Executive Officer

 cc:
 Philip Nickson, Esq., Monte Rosa Therapeutics, Inc.
 Robert Puopolo, Esq., Goodwin Procter LLP
 Kristen McCarthy, Esq., Goodwin Procter LLP