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Correspondence 0001193125-26-023649 from HCW Biologics Inc. (HCWB)

HCW Biologics Inc.
Date: Jan. 27, 2026 · CIK: 0001828673 · Accession: 0001193125-26-023649

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File numbers found in text: 333-292652

Date
January 27, 2026
Author
Hing C. Wong
Form
CORRESP
Company
HCW Biologics Inc.

Letter

Re: HCW Biologics Inc. Registration Statement on Form S-1; Commission File No. 333-292652 Dear Mr. Edwards: Pursuant to Rule 461 promulgated under the Securities Act of 1933, as amended, HCW Biologics Inc. (the “Company”) hereby requests that the effectiveness of the Company’s Registration Statement on Form S-1 (File No. 333-292652), filed on January 9, 2026, be accelerated by the U.S. Securities and Exchange Commission to 3:00 p.m. Eastern Time on Thursday, January 29, 2026, or as soon thereafter as is practicable. The Company hereby authorizes James Groth or Jeny Zarmon of Clark Hill PLC to orally modify or withdraw this request for acceleration. Please contact Mr. Groth at (312) 701-6830 or Ms. Zarmon at (609) 785-2918 with any questions you may have concerning this request, and please notify them when this request for acceleration has been granted. Thank you for your courtesy and cooperation in this matter. Very truly yours,

January 27, 2026 VIA EDGAR AND E-MAIL Mr. Christopher Edwards Office of Life Sciences Division of Corporate Finance U.S. Securities and Exchange Commission 100 F. Street, N.E. Washington, DC 20549-7010

HCW BIOLOGICS INC.

By:

/s/ Hing C. Wong

Hing C. Wong, Founder and CEO HCW Biologics Inc. acceleration request for S-1 January 2026

2929 N Commerce Parkway |Miramar, Florida 33025, USA |Phone 954-842-2024 | Fax 954-842-2037 | 1

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CORRESP
 1
 filename1.htm

 CORRESP

 January 27, 2026
 VIA EDGAR AND E-MAIL
 Mr. Christopher Edwards Office of Life Sciences
 Division of Corporate Finance U.S. Securities and Exchange
Commission 100 F. Street, N.E. Washington, DC 20549-7010

 Re:
 HCW Biologics Inc. Registration Statement on Form S-1;
 Commission File No. 333-292652
 Dear Mr. Edwards: Pursuant to Rule 461 promulgated under
the Securities Act of 1933, as amended, HCW Biologics Inc. (the “Company”) hereby requests that the effectiveness of the Company’s Registration Statement on Form S-1 (File No. 333-292652), filed on January 9, 2026, be accelerated by the U.S. Securities and Exchange Commission to 3:00 p.m. Eastern Time on Thursday, January 29, 2026, or as soon thereafter as is
practicable. The Company hereby authorizes James Groth or Jeny Zarmon of Clark Hill PLC to orally modify or withdraw this request for acceleration.
Please contact Mr. Groth at (312) 701-6830 or Ms. Zarmon at (609) 785-2918 with any questions you may have concerning this request, and please notify them when
this request for acceleration has been granted. Thank you for your courtesy and cooperation in this matter.
 Very truly yours,

 HCW BIOLOGICS INC.

 By:

 /s/ Hing C. Wong

 Hing C. Wong, Founder and CEO
 HCW Biologics Inc. acceleration request for S-1 January 2026

 2929 N Commerce Parkway |Miramar, Florida 33025, USA |Phone 954-842-2024 | Fax 954-842-2037 | 1