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SEC Company Response from Transcode Therapeutics, (RNAZ) — May 15, 2026

Transcode Therapeutics, Inc.
Date: May 15, 2026 · CIK: 0001829635 · Accession: 0001104659-26-062701

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File numbers found in text: 333-295481

Date
May 15, 2026
Author
Thomas A. Fitzgerald
Form
CORRESP
Company
Transcode Therapeutics, Inc.

Letter

Re: TransCode Therapeutics, Inc. Registration Statement on Form S-1 File No. 333-295481

May 15, 2026

VIA EDGAR

United States Securities and Exchange Commission

Division of Corporation Finance

Office of Life Sciences

100 F Street, N.E.

Washington, D.C. 20549

Ladies and Gentlemen:

Pursuant to Rule 461 promulgated under the Securities Act of 1933, as amended, the undersigned registrant, TransCode Therapeutics, Inc., a Delaware corporation (the " Registrant "), hereby requests that the above-referenced Registration Statement on Form S-1 (the " Registration Statement ") be declared effective at 4:00 p.m., Eastern Time, on May 19, 2026 or as soon as practicable thereafter. Once the Registration Statement has been declared effective, please orally confirm that event with our counsel, Orrick, Herrington & Sutcliffe LLP, by calling Niki Fang at (415) 773-5540.

The Registrant hereby authorizes Niki Fang of Orrick, Herrington & Sutcliffe LLP to orally modify or withdraw this request for acceleration.

Thank you for your assistance in this matter.

Kind regards,

TRANSCODE THERAPUETICS, INC.

By: /s/ Thomas A. Fitzgerald

Name: Thomas A. Fitzgerald

Title: Chief Financial Officer

cc: Niki Fang, Orrick, Herrington & Sutcliffe LLP

Show Raw Text
CORRESP
 1
 filename1.htm

 May 15, 2026

 VIA EDGAR

 United States Securities and Exchange Commission

 Division of Corporation Finance

 Office of Life Sciences

 100 F Street, N.E.

 Washington, D.C. 20549

 Re: TransCode Therapeutics, Inc. Registration Statement on Form
S-1
File No. 333-295481

 Ladies and Gentlemen:

 Pursuant to Rule 461 promulgated
under the Securities Act of 1933, as amended, the undersigned registrant, TransCode Therapeutics, Inc., a Delaware corporation (the " Registrant "),
hereby requests that the above-referenced Registration Statement on Form S-1 (the " Registration Statement ") be declared
effective at 4:00 p.m., Eastern Time, on May 19, 2026 or as soon as practicable thereafter. Once the Registration Statement has been
declared effective, please orally confirm that event with our counsel, Orrick, Herrington & Sutcliffe LLP, by calling Niki Fang at
(415) 773-5540.

 The Registrant hereby authorizes
Niki Fang of Orrick, Herrington & Sutcliffe LLP to orally modify or withdraw this request for acceleration.

 Thank you for your assistance
in this matter.

 Kind regards,

 TRANSCODE THERAPUETICS, INC.

 By:
 /s/ Thomas A. Fitzgerald

 Name:
 Thomas A. Fitzgerald

 Title:
 Chief Financial Officer

 cc: Niki Fang, Orrick, Herrington & Sutcliffe LLP