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SEC Comment Letter 0000000000-24-013719 to Maze Therapeutics, Inc. (MAZE) (CIK 0001842295) (MAZE)

Maze Therapeutics, Inc. (MAZE) (CIK 0001842295)
Date: Dec. 13, 2024 · CIK: 0001842295 · Accession: 0000000000-24-013719

AI Filing Summary & Sentiment

Date
December 13, 2024
Author
Not clearly detected
Form
UPLOAD
Company
Maze Therapeutics, Inc. (MAZE) (CIK 0001842295)

Letter

December 13, 2024 Jason Coloma, Ph.D. Chief Executive Officer Maze Therapeutics, Inc. 171 Oyster Point Blvd. Suite 300 South San Francisco, CA 94080 Re:Maze Therapeutics, Inc. Amendment No. 5 to Draft Registration Statement on Form S-1 Submitted December 6, 2024 CIK 0001842295 Dear Jason Coloma Ph.D.: We have reviewed your amended draft registration statement and have the following comments. Please respond to this letter by providing the requested information and either submitting an amended draft registration statement or publicly filing your registration statement on EDGAR. If you do not believe a comment applies to your facts and circumstances or do not believe an amendment is appropriate, please tell us why in your response. After reviewing the information you provide in response to this letter and your amended draft registration statement or filed registration statement, we may have additional comments. Unless we note otherwise, any references to prior comments are to comments in our August 26, 2024 letter. Amendment No. 5 to Draft Registration Statement on Form S-1 Prospectus Summary Our Clinical Pipeline, page 2 1.We note that MZE829 has not yet initiated its Phase 2 trial. Please explain why the arrow in the pipeline table extends into the column for Phase 2. Business MZE829 Phase 1 results, page 129 Please provide information in relation to the number 1 superscript in Figure 11, or 2.

December 13, 2024 Page 2 remove. Please contact Sasha Parikh at 202-551-3627 or Kevin Vaughn at 202-551-3494 if you have questions regarding comments on the financial statements and related matters. Please contact Jimmy McNamara at 202-551-7349 or Suzanne Hayes at 202-551- 3675 with any other questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc:Amanda Rose

Show Raw Text
December 13, 2024
Jason Coloma, Ph.D.
Chief Executive Officer
Maze Therapeutics, Inc.
171 Oyster Point Blvd.
Suite 300
South San Francisco, CA 94080
Re:Maze Therapeutics, Inc.
Amendment No. 5 to Draft Registration Statement on Form S-1
Submitted December 6, 2024
CIK 0001842295
Dear Jason Coloma Ph.D.:
            We have reviewed your amended draft registration statement and have the following
comments.
            Please respond to this letter by providing the requested information and either
submitting an amended draft registration statement or publicly filing your registration
statement on EDGAR. If you do not believe a comment applies to your facts and
circumstances or do not believe an amendment is appropriate, please tell us why in your
response.
            After reviewing the information you provide in response to this letter and your
amended draft registration statement or filed registration statement, we may have additional
comments. Unless we note otherwise, any references to prior comments are to comments in
our August 26, 2024 letter.
Amendment No. 5 to Draft Registration Statement on Form S-1
Prospectus Summary
Our Clinical Pipeline, page 2
1.We note that MZE829 has not yet initiated its Phase 2 trial. Please explain why the
arrow in the pipeline table extends into the column for Phase 2.
Business
MZE829 Phase 1 results, page 129
Please provide information in relation to the number 1 superscript in Figure 11, or 2.

December 13, 2024
Page 2
remove.
            Please contact Sasha Parikh at 202-551-3627 or Kevin Vaughn at 202-551-3494 if
you have questions regarding comments on the financial statements and related
matters. Please contact Jimmy McNamara at 202-551-7349 or Suzanne Hayes at 202-551-
3675 with any other questions.
Sincerely,
Division of Corporation Finance
Office of Life Sciences
cc:Amanda Rose