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CORRESP Filing

ALUMIS INC.
Date: Aug. 15, 2025 · CIK: 0001847367 · Accession: 0001104659-25-079224

Offering / Registration Process

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File numbers found in text: 333-288510

Date
August 15, 2025
Author
President &
Form
CORRESP
Company
ALUMIS INC.

Letter

ALUMIS INC.

280 East Grand Avenue

South San Francisco, CA 94080

(650) 231-6625

August 15, 2025

Via EDGAR

U.S. Securities and Exchange Commission

Division of Corporation Finance

Office of Life Sciences

100 F Street, N.E.

Washington, D.C. 20549

Re: Alumis Inc.

Registration Statement on Form S-3

Filed July 3, 2025

File No. 333-288510

Ladies and Gentlemen:

In accordance with Rule 461 under the Securities Act of 1933, as amended, the undersigned registrant (the " Registrant ") hereby requests that the U.S. Securities and Exchange Commission (the " Commission ") take appropriate action to cause the Registration Statement on Form S-3 (File No. 333-288510) (the " Registration Statement ") to become effective on Tuesday, August 19, 2025, at 4:00 p.m., Eastern Time, or as soon as practicable thereafter, or at such later time as the Registrant may orally request via telephone call to the staff of the Commission. The Registrant hereby authorizes Chadwick Mills of Cooley LLP, counsel to the Registrant, to make such request on its behalf.

Once the Registration Statement has been declared effective, please orally confirm that event with Chadwick Mills of Cooley LLP, counsel to the Registrant, at (650) 843-5654, or in his absence Christine Turner of Cooley LLP at (720) 566-4163.

Very truly yours,
ALUMIS
INC.

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CORRESP
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 filename1.htm

 ALUMIS
INC.

 280 East Grand Avenue

 South San Francisco, CA 94080

 (650) 231-6625

 August 15, 2025

 Via EDGAR

 U.S. Securities and Exchange Commission

 Division of Corporation Finance

 Office of Life Sciences

 100 F Street, N.E.

 Washington, D.C. 20549

 Re: Alumis Inc.

 Registration Statement on Form S-3

 Filed July 3, 2025

 File No. 333-288510

 Ladies and Gentlemen:

 In accordance with Rule 461 under the Securities Act of 1933,
as amended, the undersigned registrant (the " Registrant ") hereby requests that the U.S. Securities and Exchange
Commission (the " Commission ") take appropriate action to cause the Registration Statement on Form S-3 (File
No. 333-288510) (the " Registration Statement ") to become effective on Tuesday, August 19, 2025, at
4:00 p.m., Eastern Time, or as soon as practicable thereafter, or at such later time as the Registrant may orally request via telephone
call to the staff of the Commission. The Registrant hereby authorizes Chadwick Mills of Cooley LLP, counsel to the Registrant, to make
such request on its behalf.

 Once the Registration Statement has been declared effective, please
orally confirm that event with Chadwick Mills of Cooley LLP, counsel to the Registrant, at (650) 843-5654, or in his absence Christine
Turner of Cooley LLP at (720) 566-4163.

 Very truly yours,

 ALUMIS
INC.

 By:
 /s/ Martin Babler

 Name:
 Martin
Babler

 Title:
 President &
Chief Executive Officer

 cc: Kristin VanderPas, Cooley LLP

 Chadwick Mills, Cooley LLP

 Christine Turner, Cooley LLP