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CORRESP Filing

CERO THERAPEUTICS HOLDINGS, INC.
Date: Dec. 9, 2025 · CIK: 0001870404 · Accession: 0001213900-25-119655

Offering / Registration Process

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File numbers found in text: 333-291984

Date
December 9, 2025
Author
/s/ Chris Ehrlich
Form
CORRESP
Company
CERO THERAPEUTICS HOLDINGS, INC.

Letter

VIA EDGAR Division of Corporation Finance Office of Life Sciences Acceleration Request for Registration Statement on Form S-1 File No. 333-291984 Requested Date: December 11, 2025 Requested Time: 4:00 p.m. Eastern Time

Dear Ladies and Gentlemen,

Pursuant to Rule 461 under the Securities Act of 1933, as amended, CERo Therapeutics Holdings, Inc. hereby requests that the effective date of the above-referenced registration statement (the " Registration Statement ") be accelerated to December 11, 2025, at 4:00 p.m., Eastern Time, or as soon thereafter as practicable, unless we or our outside counsel, Goodwin Procter LLP (" Goodwin "), request by telephone that such Registration Statement be declared effective at some other time.

Once the Registration Statement is effective, please orally confirm the event with our counsel, Goodwin, by calling Stephen Davis at (212) 813-8804. We also respectfully request that a copy of the written order from the Securities and Exchange Commission verifying the effective time and date of the Registration Statement be sent to our counsel, Goodwin, Attention: Stephen Davis, by email at SDavis@goodwinlaw.com.

If you have any questions regarding this request, please contact Stephen Davis of Goodwin at (212) 813-8804.

Sincerely,
CERo Therapeutics Holdings, Inc.

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CORRESP
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 filename1.htm

 CERo Therapeutics Holdings, Inc.

 201 Haskins Way, Suite 230

 South San Francisco, CA 94080

 December 9, 2025

 VIA EDGAR

 Division of Corporation Finance

 Office of Life Sciences

 U.S. Securities and Exchange Commission

 100 F Street, N.E.

 Washington, D.C. 20549

 Re: CERo Therapeutics Holdings, Inc.

 Acceleration Request for Registration Statement
 on Form S-1

 File No. 333-291984

 Requested Date: December 11, 2025

 Requested Time: 4:00 p.m. Eastern Time

 Dear Ladies and Gentlemen,

 Pursuant to Rule 461 under the Securities Act of 1933,
as amended, CERo Therapeutics Holdings, Inc. hereby requests that the effective date of the above-referenced registration statement (the
" Registration Statement ") be accelerated to December 11, 2025, at 4:00 p.m., Eastern Time, or as soon thereafter as
practicable, unless we or our outside counsel, Goodwin Procter LLP (" Goodwin "), request by telephone that such Registration
Statement be declared effective at some other time.

 Once the Registration Statement is effective, please
orally confirm the event with our counsel, Goodwin, by calling Stephen Davis at (212) 813-8804. We also respectfully request that a copy
of the written order from the Securities and Exchange Commission verifying the effective time and date of the Registration Statement be
sent to our counsel, Goodwin, Attention: Stephen Davis, by email at SDavis@goodwinlaw.com.

 If you have any questions regarding this request, please
contact Stephen Davis of Goodwin at (212) 813-8804.

 Sincerely,

 CERo Therapeutics Holdings, Inc.

 /s/ Chris Ehrlich

 Name: 	Chris Ehrlich Title: 	Chief Executive Officer

 cc: Stephen M. Davis, Esq., Goodwin Procter LLP

 Jeffrey A. Letalien, Esq., Goodwin Procter LLP