SecProbe.io

CORRESP
 1
 filename1.htm

 July
10, 2025

 VIA
EDGAR

 U.S.
Securities and Exchange Commission

 Division
of Corporation Finance

 100
F Street NE

 Washington,
D.C. 20549

 Attention:
Chris Edwards

 Re:
 60 Degrees Pharmaceuticals,
 Inc.

 Registration Statement
 on Form S-1

 File No. 333-288550

 Filed July 7, 2025

 Ladies
and Gentlemen:

 60
Degrees Pharmaceuticals, Inc. (the "Company") hereby requests acceleration of the effective date of the above-referenced
Registration Statement so that it may become effective at 5:15 p.m. Eastern Time on July 14, 2025, or as soon as practicable thereafter,
unless the Company notifies you otherwise prior to such time.

 In
making this acceleration request, the Company acknowledges that:

 i) should
 the Securities and Exchange Commission (the "Commission") or the staff, acting
 pursuant to delegated authority, declare the Registration Statement effective, it does not
 foreclose the Commission from taking any action with respect to the Registration Statement;

 ii) the
 action of the Commission or the staff, acting pursuant to delegated authority, in declaring
 the Registration Statement effective, does not relieve the Company from its full responsibility
 for the adequacy of the disclosure in the Registration Statement; and

 iii) the
 Company may not assert comments of the Commission or the staff and the declaration of effectiveness
 of the Registration Statement as a defense in any proceeding initiated by the Commission
 or any person under the federal securities laws of the United States.

 Once
the Registration Statement has been declared effective, please confirm orally that event with our counsel, Sichenzia Ross Ference Carmel
LLP, by contacting Ross Carmel, Esq. at (646) 838-1310 or rcarmel@srfc.law.

 Very truly yours,

 /s/
Geoffrey S. Dow

 Geoffrey S. Dow

 Chief Executive Officer