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Correspondence 0001193125-23-132460 from ACELYRIN, Inc. (SLRN) (CIK 0001962918)

ACELYRIN, Inc. (SLRN) (CIK 0001962918)
Date: May 2, 2023 · CIK: 0001962918 · Accession: 0001193125-23-132460

AI Filing Summary & Sentiment

File numbers found in text: 333-271244

Date
May 2, 2023
Author
Executive Director
Form
CORRESP
Company
ACELYRIN, Inc. (SLRN) (CIK 0001962918)

Letter

Morgan Stanley & Co. LLC

1585 Broadway

New York, New York 10036

Jefferies LLC

520 Madison Avenue

New York, New York 10022

Cowen and Company, LLC

599 Lexington Avenue

New York, New York 10022

Piper Sandler & Co.

800 Nicollet Mall, Suite 800

Minneapolis, Minnesota 55402

May 2, 2023

VIA EDGAR

U.S. Securities and Exchange Commission

Division of Corporation Finance

Office of Life Sciences

100 F Street, N.E.

Washington, D.C. 20549

Attn: Cindy Polynice, Suzanne Hayes, Ibolya Ignat, Vanessa Robertson

Re: ACELYRIN, INC.

Registration Statement on Form S-1, as amended (File No. 333-271244)

Request for Acceleration of Effective Date

Ladies and Gentlemen:

In accordance with Rule 461 under the Securities Act of 1933, as amended (the “Act”), we, as representatives of the several underwriters, hereby join in the request of ACELYRIN, INC. (the “Company”) for acceleration of the effective date of the above-referenced Registration Statement on Form S-1 so that it becomes effective as of 4:00 p.m. Eastern time on May 4, 2023, or as soon thereafter as practicable, or at such other time as the Company or its outside counsel, Cooley LLP, request by telephone that such Registration Statement be declared effective.

Pursuant to Rule 460 under the Act, we, as representatives of the several underwriters, wish to advise you that there will be distributed to each underwriter or dealer, who is reasonably anticipated to participate in the distribution of the security, as many copies of the proposed form of preliminary prospectus as appears to be reasonable to secure adequate distribution of the preliminary prospectus.

We, the undersigned, as representatives of the several underwriters, have complied and will comply, and we have been informed by the participating underwriters that they have complied and will comply, with the requirements of Rule 15c2-8 under the Securities Exchange Act of 1934, as amended.

Very truly yours,
Morgan Stanley & Co. LLC

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CORRESP
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CORRESP

 Morgan Stanley & Co. LLC

1585 Broadway

 New York, New York 10036

Jefferies LLC

 520 Madison Avenue

New York, New York 10022

 Cowen and Company, LLC

599 Lexington Avenue

 New York, New York 10022

Piper Sandler & Co.

 800 Nicollet Mall, Suite 800

Minneapolis, Minnesota 55402

 May 2, 2023

VIA EDGAR

 U.S. Securities and Exchange Commission

 Division of Corporation Finance

 Office of Life Sciences

 100 F Street, N.E.

 Washington, D.C. 20549

Attn: Cindy Polynice, Suzanne Hayes, Ibolya Ignat, Vanessa Robertson

Re:
 ACELYRIN, INC.

Registration Statement on Form S-1, as amended (File No. 333-271244)

Request for Acceleration of Effective Date

Ladies and Gentlemen:

 In accordance with Rule
461 under the Securities Act of 1933, as amended (the “Act”), we, as representatives of the several underwriters, hereby join in the request of ACELYRIN, INC. (the “Company”) for acceleration of the effective date
of the above-referenced Registration Statement on Form S-1 so that it becomes effective as of 4:00 p.m. Eastern time on May 4, 2023, or as soon thereafter as practicable, or at such other time as the
Company or its outside counsel, Cooley LLP, request by telephone that such Registration Statement be declared effective.

 Pursuant to Rule
460 under the Act, we, as representatives of the several underwriters, wish to advise you that there will be distributed to each underwriter or dealer, who is reasonably anticipated to participate in the distribution of the security, as many copies
of the proposed form of preliminary prospectus as appears to be reasonable to secure adequate distribution of the preliminary prospectus.

We, the undersigned, as representatives of the several underwriters, have complied and will comply, and we have been informed by the
participating underwriters that they have complied and will comply, with the requirements of Rule 15c2-8 under the Securities Exchange Act of 1934, as amended.

Very truly yours,

Morgan Stanley & Co. LLC

Jefferies LLC

Cowen and Company, LLC

Piper Sandler & Co.

Acting severally on behalf of themselves and the several Underwriters named in Schedule I hereto

By:

Morgan Stanley & Co. LLC

By:

 /s/ Frank Tang

Name:

Frank Tang

Title:

Executive Director

By:

Jefferies LLC

By:

 /s/ Michael Brinkman

Name:

Michael Brinkman

Title:

Managing Director, Joint US Head of Biopharmaceuticals

By:

Cowen and Company, LLC

By:

 /s/ Bill Follis

Name:

Bill Follis

Title:

Managing Director

By:

Piper Sandler & Co.

By:

 /s/ Chad Huber

Name:

Chad Huber

Title:

Co-Head of ECM

 [Signature Page to the Underwriters’ Acceleration Request]

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