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CORRESP Filing

Silexion Therapeutics Corp
Date: Sept. 9, 2025 · CIK: 0002022416 · Accession: 0001178913-25-003278

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File numbers found in text: 333-290074

Date
September 9, 2025
Author
Ilan Hadar
Form
CORRESP
Company
Silexion Therapeutics Corp

Letter

Re:

Silexion Therapeutics Corp. 12 Abba Hillel Road Ramat Gan, Israel 5250606

September 9, 2025

Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549

Silexion Therapeutics Corp.

Registration Statement on Form S-1 Filed September 5, 2025 File No. 333-290074

VIA EDGAR

Ladies and Gentlemen:

Pursuant to Rule 461 under the Securities Act of 1933, as amended, Silexion Therapeutics Corp. (the “ Company ”) hereby respectfully requests that the effectiveness of the Registration Statement on Form S-1 (File No. 333-290074) of the Company (the “ Registration Statement ”) be accelerated so that the Company’s Registration Statement will become effective at 9:00 a.m., Eastern Time, on September 11, 2025 or as soon thereafter as may be practicable.

The undersigned respectfully requests that it be notified of the effectiveness of the Registration Statement by telephone call to our counsel, Greenberg Traurig, LLP, by calling Gary Emmanuel at (212) 801-9337. The Company hereby authorizes Mr. Emmanuel to orally modify or withdraw this request for acceleration.

Very truly yours,
SILEXION THERAPEUTICS CORP

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CORRESP
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 Silexion Therapeutics Corp.
 12 Abba Hillel Road
 Ramat Gan, Israel 5250606

 September 9, 2025

 Securities and Exchange Commission
 Division of Corporation Finance
 100 F Street, N.E.
 Washington, D.C. 20549

 Re:

 Silexion Therapeutics Corp.

 Registration Statement on Form S-1
 Filed September 5, 2025
 File No. 333-290074

 VIA EDGAR

 Ladies and Gentlemen:

 Pursuant to Rule 461 under the Securities Act of 1933, as amended, Silexion Therapeutics Corp. (the “ Company ”) hereby respectfully requests that the effectiveness of the Registration Statement on Form S-1 (File No. 333-290074) of the Company (the “ Registration Statement ”) be accelerated so that the Company’s Registration Statement will become effective at 9:00 a.m., Eastern Time, on September
 11, 2025 or as soon thereafter as may be practicable.

 The undersigned respectfully requests that it be notified of the effectiveness of the Registration Statement by
 telephone call to our counsel, Greenberg Traurig, LLP, by calling Gary Emmanuel at (212) 801-9337. The Company hereby authorizes Mr. Emmanuel to orally modify or withdraw this request for acceleration.

 Very truly yours,

 SILEXION THERAPEUTICS CORP

 By:

 /s/ Ilan Hadar

 Name:

 Ilan Hadar

 Title:

 Chief Executive Officer

 cc: Gary Emmanuel (Greenberg Traurig, LLP)