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CORRESP Filing

Silexion Therapeutics Corp
Date: Sept. 30, 2025 · CIK: 0002022416 · Accession: 0001178913-25-003421

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File numbers found in text: 333-290544

Date
September 30, 2025
Author
/s/ Ilan Hadar
Form
CORRESP
Company
Silexion Therapeutics Corp

Letter

Attention: Jason Drory Silexion Therapeutics Corp Registration Statement on Form S-3 Filed September 26, 2025 SEC File Number 333-290544

Re:

Dear Mr. Drory:

Pursuant to Rule 461 under the Securities Act of 1933, as amended, Silexion Therapeutics Corp hereby requests that the effective date of the above-referenced Registration Statement on Form S-3 be accelerated so that it will become effective at 5:00 p.m., Eastern Time on Tuesday, September 30, 2025, or as soon as practicable thereafter.

Please contact Gary Emmanuel, Esq., Greenberg Traurig, LLP, our U.S. legal counsel, at (212) 801‑9337 or Gary.Emmanuel@gtlaw.com , or Jonathan M. Nathan, Adv., Meitar Law Offices, our outside (Israeli) legal counsel, at +972-52-312-5574 or jonathann@meitar.com , with any questions, and please notify either of them when this request for acceleration has been granted.

Sincerely,
/s/ Ilan Hadar

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CORRESP
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 Silexion Therapeutics Corp
 12 Abba Hillel Road
 Ramat Gan, Israel 5250606
 Telephone: +972-3-756-4999

 September 30, 2025
 VIA EDGAR

 U.S. Securities and Exchange Commission
 Division of Corporation Finance
 Office of Life Sciences
 100 F Street, NE
 Washington, DC 20549

 Attention: Jason Drory

 Re:

 Silexion Therapeutics Corp

 Registration Statement on Form S-3

 Filed September 26, 2025
 SEC File Number 333-290544

 Dear Mr. Drory:

 Pursuant to Rule 461 under the Securities Act of 1933, as amended, Silexion Therapeutics Corp hereby requests that the effective date of the above-referenced Registration Statement on Form S-3 be
 accelerated so that it will become effective at 5:00 p.m., Eastern Time on Tuesday, September 30, 2025, or as soon as practicable thereafter.

 Please contact Gary Emmanuel, Esq., Greenberg Traurig, LLP, our U.S. legal counsel,   at (212) 801‑9337 or Gary.Emmanuel@gtlaw.com , or Jonathan M.
 Nathan, Adv., Meitar Law Offices, our outside (Israeli) legal counsel, at +972-52-312-5574 or jonathann@meitar.com , with any questions, and please notify either of them when this request for acceleration has been granted.

 Sincerely,

 /s/ Ilan Hadar

 Ilan Hadar

 Chief Executive Officer

 CC:

 Mirit Horenshtein Hadar

 Silexion Therapeutics Corp

 Gary Emmanuel, Esq.
 Greenberg Traurig, LLP

 Jonathan M. Nathan, Adv.
 Meitar Law Offices