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SEC Company Response from BIOCRYST PHARMACEUTICALS (BCRX) — Dec 16, 2025

BIOCRYST PHARMACEUTICALS INC
Date: Dec. 16, 2025 · CIK: 0000882796 · Accession: 0001140361-25-045599

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File numbers found in text: 333-291678

Date
December 16, 2025
Author
By
Form
CORRESP
Company
BIOCRYST PHARMACEUTICALS INC

Letter

Re:

December 16, 2025

VIA EDGAR

United States Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Attn: Lauren Hamill

BioCryst Pharmaceuticals, Inc.

Amendment No. 1 to Registration Statement on Form S-4

Filed December 15, 2025

File No. 333-291678

Ladies and Gentlemen:

Pursuant to Rule 461 under the Securities Act of 1933, as amended, BioCryst Pharmaceuticals, Inc. hereby requests that the effective date of its Registration Statement on Form S-4 (File No. 333-291678) be accelerated by the Securities and Exchange Commission to December 18, 2025 at 9:00 a.m., Eastern Time, or as soon as practicable thereafter.

Should you have any questions or comments regarding the foregoing, please contact Matthew T. Gehl of Covington & Burling LLP at (212) 841-1113. In addition, please notify Mr. Gehl by telephone when this request for acceleration has been granted.

Sincerely,
BIOCRYST PHARMACEUTICALS, INC.

Show Raw Text
CORRESP
 1
 filename1.htm

 December 16, 2025

 VIA EDGAR

 United States Securities and Exchange Commission
 Division of Corporation Finance
 100 F Street, N.E.
 Washington, D.C. 20549
 Attn: Lauren Hamill

 Re:

 BioCryst Pharmaceuticals, Inc.

 Amendment No. 1 to Registration Statement on Form S-4

 Filed December 15, 2025

 File No. 333-291678

 Ladies and Gentlemen:

 Pursuant to Rule 461 under the Securities Act of 1933, as amended, BioCryst Pharmaceuticals, Inc. hereby requests that the effective date
 of its Registration Statement on Form S-4 (File No. 333-291678) be accelerated by the Securities and Exchange Commission to December 18, 2025 at 9:00 a.m., Eastern Time, or as soon as practicable thereafter.

 Should you have any questions or comments regarding the foregoing, please contact Matthew T. Gehl of Covington & Burling LLP at (212)
 841-1113. In addition, please notify Mr. Gehl by telephone when this request for acceleration has been granted.

 Sincerely,

 BIOCRYST PHARMACEUTICALS, INC.

 By:

 /s/ Jon P. Stonehouse

 Jon P. Stonehouse

 Chief Executive Officer

 cc: Alane Barnes, BioCryst Pharmaceuticals, Inc.
 Ben Harshbarger, Astria Therapeutics, Inc.
 Jack S. Bodner, Covington & Burling LLP
 Andrew W. Ment, Covington & Burling LLP
 Matthew T. Gehl, Covington & Burling LLP
 Charles A. Dobb, Covington & Burling LLP
 Rosemary G. Reilly, Sidley Austin LLP
 John H. Butler, Sidley Austin LLP
 Sally Wagner Partin, Sidley Austin LLP