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CORRESP Filing

PLUS THERAPEUTICS, INC.
Date: Aug. 12, 2025 · CIK: 0001095981 · Accession: 0001193125-25-179175

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File numbers found in text: 333-289526

Date
August 12, 2025
Author
Andrew Sims
Form
CORRESP
Company
PLUS THERAPEUTICS, INC.

Letter

Re: Plus Therapeutics, Inc. Registration Statement on Form S-1 filed on August 12, 2025 File No. 333-289526 Request for Acceleration of Effective Date Ladies and Gentlemen: Pursuant to Rule 461 of the General Rules and Regulations under the Securities Act of 1933, as amended, Plus Therapeutics, Inc. hereby requests for acceleration of the effective date of the above-referenced registration statement, as amended, so that it becomes effective as of 5:30 p.m. Eastern Time on Thursday, August 14, 2025, or as soon thereafter as possible. [Signature Page to Follow]

August 12, 2025 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549

Very truly yours,
Plus Therapeutics, Inc.

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CORRESP
 1
 filename1.htm

 CORRESP

 August 12, 2025
 VIA EDGAR U.S. Securities and Exchange
Commission Division of Corporation Finance 100 F Street,
N.E. Washington, D.C. 20549

 Re:
 Plus Therapeutics, Inc.
 Registration Statement on Form S-1 filed on August 12, 2025
 File No. 333-289526
 Request for Acceleration of Effective Date
 Ladies and Gentlemen: Pursuant to Rule 461 of the General
Rules and Regulations under the Securities Act of 1933, as amended, Plus Therapeutics, Inc. hereby requests for acceleration of the effective date of the above-referenced registration statement, as amended, so that it becomes effective as of
5:30 p.m. Eastern Time on Thursday, August 14, 2025, or as soon thereafter as possible. [Signature Page to Follow]

 Very truly yours,

 Plus Therapeutics, Inc.

 By:

 /s/ Andrew Sims

 Name: Andrew Sims

 Title: Chief Financial Officer
 cc: Aaron M. Schleicher, Sullivan & Worcester LLP
 [Signature Page to Acceleration Request]