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Correspondence 0001193125-26-009088 from CERENOME, INC. (PSTV)

CERENOME, INC.
Date: Jan. 9, 2026 · CIK: 0001095981 · Accession: 0001193125-26-009088

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File numbers found in text: 333-292637

Date
January 9, 2026
Author
LAKE STREET CAPITAL MARKETS, LLC
Form
CORRESP
Company
CERENOME, INC.

Letter

Re: Plus Therapeutics, Inc.

January 9, 2026 VIA EDGAR TRANSMISSION Division of Corporate Finance United States Securities and Exchange Commission 100 F Street, N.E. Washington, D.C. 20549-6010

Registration Statement on Form S-1 (Registration No. 333-292637)

Request for Acceleration of Effective Date Ladies and gentlemen: In accordance with Rule 461 under the Securities Act of 1933, as amended (the “Act”), Lake Street Capital Markets, LLC, as underwriter, hereby joins Plus Therapeutics, Inc. in requesting that the Securities and Exchange Commission take appropriate action to cause the Registration Statement on Form S-1 (File No. 333-292637) to become effective on January 13, 2026 at 5:00 p.m., Eastern Time, or as soon as practicable thereafter. Pursuant to Rule 460 under the Act, please be advised that we will take reasonable steps to secure adequate distribution of the preliminary prospectus prior to the requested effective time of the Registration Statement.

Very truly yours,
LAKE STREET CAPITAL MARKETS, LLC

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CORRESP
 1
 filename1.htm

 CORRESP

 January 9, 2026
 VIA EDGAR TRANSMISSION Division of Corporate
Finance United States Securities and Exchange Commission
 100 F Street, N.E. Washington, D.C. 20549-6010

 Re:
 Plus Therapeutics, Inc.

  
 Registration Statement on Form S-1 (Registration No. 333-292637)

  
 Request for Acceleration of Effective Date
 Ladies and gentlemen: In accordance with Rule
461 under the Securities Act of 1933, as amended (the “Act”), Lake Street Capital Markets, LLC, as underwriter, hereby joins Plus Therapeutics, Inc. in requesting that the Securities and Exchange Commission take appropriate action to
cause the Registration Statement on Form S-1 (File No. 333-292637) to become effective on January 13, 2026 at 5:00 p.m., Eastern Time, or as soon as
practicable thereafter. Pursuant to Rule 460 under the Act, please be advised that we will take reasonable steps to secure adequate
distribution of the preliminary prospectus prior to the requested effective time of the Registration Statement.

 Very truly yours,

 LAKE STREET CAPITAL MARKETS, LLC

 By:

 /s/ Michael Townley

 Name:

 Michael Townley

 Title:

 Head of Investment Banking

 cc:
 Jonathan Zimmerman, Esq., Faegre Drinker Biddle & Reath LLP