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CORRESP Filing

ONCOLYTICS BIOTECH INC
Date: Aug. 27, 2025 · CIK: 0001129928 · Accession: 0001104659-25-084052

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File numbers found in text: 333-289819

Date
August 27, 2025
Author
Kirk Look
Form
CORRESP
Company
ONCOLYTICS BIOTECH INC

Letter

ONCOLYTICS BIOTECH INC.

Suite 804, 322 11th Avenue SW

Calgary, Alberta, Canada, T2R 0C5

VIA EDGAR

August 27, 2025

United States Securities and Exchange Commission

Division of Corporation Finance

Office of Life Sciences

100 F Street, N.E.

Washington, D.C. 20549

Attention:

Tyler Howes

Re:

Oncolytics Biotech Inc.

Registration Statement on Form F-3

File No. 333-289819

To the addressee set forth above:

Pursuant to Rule 461 of the U.S. Securities Act of 1933, as amended, Oncolytics Biotech Inc. (the "Company") hereby requests acceleration of the effective date of its registration statement on Form F-3 (File No. 333-289819) (the "Registration Statement"), to 4:00 p.m. Eastern Time on August 29, 2025, or as soon thereafter as practicable.

Please contact Christopher J. Clark of Latham & Watkins LLP, special U.S. counsel to the Company, at (202) 637-2374 or Christopher.J.Clark@lw.com, as soon as the Registration Statement has been declared effective, or if you have any other questions or concerns regarding this matter.

Very truly yours,
ONCOLYTICS BIOTECH INC.

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CORRESP
 1
 filename1.htm

 ONCOLYTICS BIOTECH INC.

 Suite 804, 322 11th Avenue SW

 Calgary, Alberta, Canada, T2R 0C5

 VIA EDGAR

 August 27, 2025

 United States Securities and Exchange Commission

 Division of Corporation Finance

 Office of Life Sciences

 100 F Street, N.E.

 Washington, D.C. 20549

 Attention:

 Tyler Howes

 Re:

 Oncolytics
Biotech Inc.

 Registration Statement on Form
F-3

 File No. 333-289819

 To the addressee set forth above:

 Pursuant to Rule 461 of the
U.S. Securities Act of 1933, as amended, Oncolytics Biotech Inc. (the "Company") hereby requests acceleration of the effective
date of its registration statement on Form F-3 (File No. 333-289819) (the "Registration Statement"), to 4:00 p.m. Eastern
Time on August 29, 2025, or as soon thereafter as practicable.

 Please contact Christopher
J. Clark of Latham & Watkins LLP, special U.S. counsel to the Company, at (202) 637-2374 or Christopher.J.Clark@lw.com, as soon as
the Registration Statement has been declared effective, or if you have any other questions or concerns regarding this matter.

 Very truly yours,

 ONCOLYTICS BIOTECH INC.

 By:
 /s/ Kirk Look

 Name:
 Kirk Look

 Title:
 Chief Financial Officer

 cc: 	Christopher J. Clark, Esq., Latham & Watkins LLP