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UPLOAD Filing

ORAGENICS INC
Date: Jan. 27, 2026 · CIK: 0001174940 · Accession: 0000000000-26-000820

Regulatory Compliance Offering / Registration Process Financial Reporting

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File numbers found in text: 333-292880

Date
January 27, 2026
Author
Janet Huffman
Form
UPLOAD
Company
ORAGENICS INC

Letter

January 27, 2026 Janet Huffman Chief Executive Officer Oragenics, Inc. 9015 Town Center Parkway, Suite 143 Lakewood Ranch, FL 34202 Re:Oragenics, Inc. Registration Statement of Form S-3 Filed January 22, 2026 File No. 333-292880 Dear Janet Huffman: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Lauren Hamill at 303-844-1008 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc:Julio Esquivel

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January 27, 2026
Janet Huffman
Chief Executive Officer
Oragenics, Inc.
9015 Town Center Parkway, Suite 143
Lakewood Ranch, FL 34202
Re:Oragenics, Inc.
Registration Statement of Form S-3
Filed January 22, 2026
File No. 333-292880
Dear Janet Huffman:
            This is to advise you that we have not reviewed and will not review your registration
statement.
            Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you
that the company and its management are responsible for the accuracy and adequacy of their
disclosures, notwithstanding any review, comments, action or absence of action by the staff.
            Please contact Lauren Hamill at 303-844-1008 with any questions.
Sincerely,
Division of Corporation Finance
Office of Life Sciences
cc:Julio Esquivel