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CORRESP Filing

ORAGENICS INC
Date: March 19, 2026 · CIK: 0001174940 · Accession: 0001493152-26-011693

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File numbers found in text: 333-292880

Date
March 19, 2026
Author
Huffman
Form
CORRESP
Company
ORAGENICS INC

Letter

VIA EDGAR United States Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences Re: Oragenics, Inc. (the "Company") Registration Statement on Form S-3/A File No. 333-292880 Request for Acceleration

Dear Ms. Hamill:

In accordance with Rule 461 of Regulation C promulgated under the Securities Act of 1933, as amended, the undersigned respectfully requests that the effective date of the above referenced Registration Statement on Form S-3/A be accelerated so that it will be declared effective at 4:00 p.m., Eastern Time, on March 20, 2026, or as soon thereafter as is practicable.

Once the Registration Statement has been declared effective, please confirm that event with our counsel, Julio Esquivel, of Shumaker, Loop & Kendrick, LLP, at (813) 227-2325.

Very truly yours,
By:
/s/Janet
Huffman

Show Raw Text
CORRESP
 1
 filename1.htm

 Oragenics,
Inc.

 9015
Town Center Parkway, Suite 143

 Lakewood
Ranch, FL 34202

 March
19, 2026

 VIA
EDGAR

 United
States Securities and Exchange Commission

 Division
of Corporation Finance

 Office
of Life Sciences

 100
F Street, N.E.

 Washington,
D.C. 20549-3628

 Attn: Lauren
Hamill, Division of Corporation Finance

 Re:
 Oragenics, Inc. (the
 "Company")

 Registration Statement
 on Form S-3/A

 File No. 333-292880

 Request for Acceleration

 Dear
Ms. Hamill:

 In
accordance with Rule 461 of Regulation C promulgated under the Securities Act of 1933, as amended, the undersigned respectfully requests
that the effective date of the above referenced Registration Statement on Form S-3/A be accelerated so that it will be declared effective
at 4:00 p.m., Eastern Time, on March 20, 2026, or as soon thereafter as is practicable.

 Once
the Registration Statement has been declared effective, please confirm that event with our counsel, Julio Esquivel, of Shumaker, Loop
& Kendrick, LLP, at (813) 227-2325.

 Very truly yours,

 By:
 /s/Janet
 Huffman

 Name:
 Janet Huffman

 Title:
 Chief Executive Officer

 c: Julio C. Esquivel,
Shumaker, Loop & Kendrick, LLP