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SEC Company Response from Milestone Pharmaceuticals Inc. (MIST) (CIK 0001408443) (MIST) — May 6, 2019

Milestone Pharmaceuticals Inc. (MIST) (CIK 0001408443)
Date: May 6, 2019 · CIK: 0001408443 · Accession: 0001104659-19-027188

Offering / Registration Process Regulatory Compliance Business Model Clarity

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File numbers found in text: 333-230846

Date
May 6, 2019
Author
By
Form
CORRESP
Company
Milestone Pharmaceuticals Inc. (MIST) (CIK 0001408443)

Letter

VIA EDGAR United States Securities and Exchange Commission Division of Corporation Finance Re: Milestone Pharmaceuticals Inc. Acceleration Request for Registration Statement on Form S-1 File No. 333-230846

Dear Sir/Madam:

Pursuant to Rule 460 of the General Rules and Regulations under the Securities Act of 1933, as amended (the “Act”), we, as representatives of the several Underwriters, wish to advise you that approximately 935 copies of the Preliminary Prospectus included in the Registration Statement on Form S-1 were distributed during the period April 29, 2019 through the date hereof, to prospective underwriters, institutions, dealers and others.

We have been informed by the participating underwriters that they will comply with the requirements of Rule 15c2-8 under the Securities Exchange Act of 1934, as amended.

In accordance with Rule 461 of the Act, we hereby join in the request of Milestone Pharmaceuticals Inc. for acceleration of the effective date of the above-named Registration Statement so that it becomes effective at 4:00 p.m. Eastern time on May 8, 2019, or as soon thereafter as practicable.

[Remainder of page intentionally left blank]

Very truly yours,
By:

Show Raw Text
CORRESP
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filename1.htm

Jefferies LLC

Cowen and Company, LLC

Piper   Jaffray & Co.

520 Madison Avenue

599 Lexington Avenue

800 Nicolette Mall

New York, NY 10022

New York, New York   10022

Minneapolis, Minnesota   55402

May 6, 2019

VIA EDGAR

United States Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

Re:

Milestone   Pharmaceuticals Inc.

Acceleration   Request for Registration Statement on Form S-1

File   No. 333-230846

Dear Sir/Madam:

Pursuant to Rule 460 of the General Rules and Regulations under the Securities Act of 1933, as amended (the “Act”), we, as representatives of the several Underwriters, wish to advise you that approximately 935 copies of the Preliminary Prospectus included in the Registration Statement on Form S-1 were distributed during the period April 29, 2019 through the date hereof, to prospective underwriters, institutions, dealers and others.

We have been informed by the participating underwriters that they will comply with the requirements of Rule 15c2-8 under the Securities Exchange Act of 1934, as amended.

In accordance with Rule 461 of the Act, we hereby join in the request of Milestone Pharmaceuticals Inc. for acceleration of the effective date of the above-named Registration Statement so that it becomes effective at 4:00 p.m. Eastern time on May 8, 2019, or as soon thereafter as practicable.

[Remainder of page intentionally left blank]

Very truly yours,

By:

JEFFERIES LLC

By:

/s/ Matthew Kim

Name: Matthew Kim

Title: Managing   Director

By:

COWEN AND COMPANY, LLC

By:

/s/ Chris Swindle

Name: Chris Swindle

Title: Managing   Director

By:

PIPER   JAFFRAY & CO.

By:

/s/ Chad Huber

Name: Chad Huber

Title: Managing   Director

[Signature page to Acceleration Request Letter]

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