SEC Company Response from Karyopharm Therapeutics Inc. (KPTI) (CIK 0001503802) (KPTI) — Feb 13, 2018
Karyopharm Therapeutics Inc. (KPTI) (CIK 0001503802)
Date: Feb. 13, 2018 · CIK: 0001503802 · Accession: 0001193125-18-042087
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File numbers found in text: 333-222726
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CORRESP 1 filename1.htm CORRESP KARYOPHARM THERAPEUTICS INC. 85 WELLS AVENUE, SECOND FLOOR NEWTON, MA 02459 February 13, 2018 Via EDGAR Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Re: Karyopharm Therapeutics Inc. Registration Statement on Form S-3 File No. 333-222726 Request for Acceleration Ladies and Gentlemen: Karyopharm Therapeutics Inc. (the “Registrant”) hereby withdraws its earlier request dated the date hereof requesting acceleration of the effective date of its Registration Statement on Form S-3 (File No. 333-222726) (the “Registration Statement”) to February 15, 2018. Pursuant to Rule 461 promulgated under the Securities Act of 1933, as amended, the Registrant hereby requests acceleration of the effective date of the Registration Statement so that it may become effective at 4:00 p.m. Eastern time on February 14, 2018, or as soon thereafter as practicable. Very truly yours, Karyopharm Therapeutics Inc. By: /s/ Christopher B. Primiano Name: Christopher B. Primiano Title: Executive Vice President, Chief Business Officer, General Counsel and Secretary