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SEC Comment Letter for OnKure Therapeutics, (OKUR) — Apr 30, 2026

OnKure Therapeutics, Inc.
Date: April 30, 2026 · CIK: 0001637715 · Accession: 0000000000-26-004422

Regulatory Compliance Financial Reporting Offering / Registration Process

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File numbers found in text: 333-295304

Date
April 30, 2026
Author
Division of
Form
UPLOAD
Company
OnKure Therapeutics, Inc.

Letter

Re: OnKure Therapeutics, Inc. Registration Statement on Form S-3 Filed April 24, 2026 File No. 333-295304 Dear Nicholas A. Saccomano:

April 30, 2026

Nicholas A. Saccomano President and Chief Executive Officer OnKure Therapeutics, Inc. 6707 Winchester Circle, Suite 400 Boulder, CO 80301

This is to advise you that we have not reviewed and will not review your registration statement.

Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff.

Please contact Chris Edwards at 202-551-6761 with any questions.

Sincerely,
Division of
Corporation Finance
Office of Life
Sciences
cc: Phillip McGill

Show Raw Text
<DOCUMENT>
<TYPE>TEXT-EXTRACT
<SEQUENCE>2
<FILENAME>filename2.txt
<TEXT>
 April 30, 2026

Nicholas A. Saccomano
President and Chief Executive Officer
OnKure Therapeutics, Inc.
6707 Winchester Circle, Suite 400
Boulder, CO 80301

 Re: OnKure Therapeutics, Inc.
 Registration Statement on Form S-3
 Filed April 24, 2026
 File No. 333-295304
Dear Nicholas A. Saccomano:

 This is to advise you that we have not reviewed and will not review your
registration
statement.

 Please refer to Rules 460 and 461 regarding requests for acceleration.
We remind you
that the company and its management are responsible for the accuracy and
adequacy of their
disclosures, notwithstanding any review, comments, action or absence of action
by the staff.

 Please contact Chris Edwards at 202-551-6761 with any questions.

 Sincerely,

 Division of
Corporation Finance
 Office of Life
Sciences
cc: Phillip McGill
</TEXT>
</DOCUMENT>